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anti-PTGES2 antibody :: Rabbit prostaglandin E synthase 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714245 anti-PTGES2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

prostaglandin E synthase 2 (PTGES2), Polyclonal Antibody

 Also Known As   

Rabbit anti-human prostaglandin E synthase 2 polyclonal Antibody

 Product Synonym Names    prostaglandin E synthase 2; PTGES2; C9orf15; FLJ14038; GBF1; MGC11289; PGES2; mPGES-2
 Product Gene Name   

anti-PTGES2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608152
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human PTGES2
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160662
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PTGES2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-PTGES2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for PTGES2. It may not necessarily be applicable to this product.
 NCBI GI #    73921741
 NCBI GeneID    80142
 NCBI Accession #    Q9H7Z7.1 [Other Products]
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 UniProt Secondary Accession #    Q53EW9; Q5SYV6; Q96GI0; Q96GL2 [Other Products]
 UniProt Related Accession #    Q9H7Z7 [Other Products]
 Molecular Weight    41,943 Da [Similar Products]
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 NCBI Official Full Name    Prostaglandin E synthase 2
 NCBI Official Synonym Full Names    prostaglandin E synthase 2
 NCBI Official Symbol    PTGES2 [Similar Products]
 NCBI Official Synonym Symbols   
GBF1; GBF-1; PGES2; C9orf15; mPGES-2
[Similar Products]
 NCBI Protein Information    prostaglandin E synthase 2; GATE-binding factor 1; microsomal prostaglandin E synthase-2; membrane-associated prostaglandin E synthase 2; gamma-interferon-activated transcriptional element-binding factor 1
 UniProt Protein Name    Prostaglandin E synthase 2
 UniProt Synonym Protein Names   
Membrane-associated prostaglandin E synthase-2; Microsomal prostaglandin E synthase 2
 Protein Family    Prostaglandin E synthase
 UniProt Gene Name    PTGES2 [Similar Products]
 UniProt Entry Name    PGES2_HUMAN
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 NCBI Summary for PTGES2    The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
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 UniProt Comments for PTGES2    PTGES2: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Belongs to the GST superfamily.

Protein type: Lipid Metabolism - arachidonic acid; Isomerase; EC 5.3.99.3; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: Golgi membrane; mitochondrion; perinuclear region of cytoplasm; integral to membrane; cytosol; nucleus

Molecular Function: electron carrier activity; DNA binding; glutathione binding; heme binding; lyase activity; protein disulfide oxidoreductase activity; prostaglandin-E synthase activity

Biological Process: secretion; cell redox homeostasis; positive regulation of transcription, DNA-dependent; prostaglandin biosynthetic process
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 Research Articles on PTGES2    1. Four single nucleotide polymorphisms in two genes in the PGE2 family, PTGES2 and PTGER4, were significantly associated with primary graft dysfunction after lung transplantation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PTGES2 antibodyPathways associated with anti-PTGES2 antibody
 Reference Product  PubMed Publications
 PTGS2 antibody  >10 publications with PTGES2 and PTGS2
 PTGES antibody  >7 publications with PTGES2 and PTGES
 PTGS1 antibody  >5 publications with PTGES2 and PTGS1
 CBR1 antibody  >2 publications with PTGES2 and CBR1
 PTGIS antibody  >2 publications with PTGES2 and PTGIS
 HPGDS antibody  >1 publications with PTGES2 and HPGDS
 TBXAS1 antibody  >1 publications with PTGES2 and TBXAS1
 PTGDS antibody  >1 publications with PTGES2 and PTGDS
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 IFN-gamma Pathway antibodies  IFN-gamma Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Prostanoid Biosynthesis Pathway antibodies  Prostanoid Biosynthesis Pathway Diagram
Diseases associated with anti-PTGES2 antibodyOrgans/Tissues associated with anti-PTGES2 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with PTGES2 and Carcinoma
 Obesity Antibodies  >2 publications with PTGES2 and Obesity
 Disease Models, Animal Antibodies  >1 publications with PTGES2 and Disease Models, Animal
 Anoxia Antibodies  >1 publications with PTGES2 and Anoxia
 Neoplasms, Experimental Antibodies  >1 publications with PTGES2 and Neoplasms, Experimental
 Insulin Resistance Antibodies  >1 publications with PTGES2 and Insulin Resistance
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with PTGES2 and Prenatal Exposure Delayed Effects
 Inflammation Antibodies  >1 publications with PTGES2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >4 publications with PTGES2 and Uterus
 Blood Antibodies  >3 publications with PTGES2 and Blood
 Embryonic Tissue Antibodies  >2 publications with PTGES2 and Embryonic Tissue
 Vascular Antibodies  >1 publications with PTGES2 and Vascular
 Mammary Gland Antibodies  >1 publications with PTGES2 and Mammary Gland
 Prostate Antibodies  >1 publications with PTGES2 and Prostate
 Lung Antibodies  >1 publications with PTGES2 and Lung
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