AAI04257.1
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UniProt Related Accession #
NCBI Official Full Name
Protein kinase (cAMP-dependent, catalytic) inhibitor gamma
NCBI Official Synonym Full Names
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
NCBI Official Synonym Symbols
NCBI Protein Information
cAMP-dependent protein kinase inhibitor gamma
UniProt Protein Name
cAMP-dependent protein kinase inhibitor gamma
UniProt Synonym Gene Names
UniProt Entry Name
IPKG_HUMAN
NCBI Summary for PKIG
This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UniProt Comments for PKIG
PKIG: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family.
Protein type: Inhibitor; Protein kinase, regulatory subunit
Chromosomal Location of Human Ortholog: 20q12-q13.1
Cellular Component: cytoplasm; nucleus
Molecular Function: cAMP-dependent protein kinase inhibitor activity
Biological Process: negative regulation of protein import into nucleus; negative regulation of transcription from RNA polymerase II promoter; signal transduction
Research Articles on PKIG
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Pathways associated with anti-PKIG antibody
Diseases associated with anti-PKIG antibody
Organs/Tissues associated with anti-PKIG antibody
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