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anti-RNF212 antibody :: Rabbit ring finger protein 212 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS712274 anti-RNF212 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ring finger protein 212 (RNF212), Polyclonal Antibody

 Also Known As   

Rabbit anti-human ring finger protein 212 polyclonal Antibody

 Product Synonym Names    ring finger protein 212; RNF212; FLJ38841; MGC120227; MGC120228; ZHP3
 Product Gene Name   

anti-RNF212 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 612042
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human RNF212
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-163304
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RNF212 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RNF212 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for RNF212. It may not necessarily be applicable to this product.
 NCBI GI #    71682031
 NCBI GeneID    285498
 NCBI Accession #    AAI01260.1 [Other Products]
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 UniProt Secondary Accession #    Q495C0; Q86W82; Q8IY99; Q8N8U7; C9J8N0 [Other Products]
 UniProt Related Accession #    Q495C1 [Other Products]
 Molecular Weight    30,357 Da [Similar Products]
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 NCBI Official Full Name    Ring finger protein 212
 NCBI Official Synonym Full Names    ring finger protein 212
 NCBI Official Symbol    RNF212 [Similar Products]
 NCBI Official Synonym Symbols   
ZHP3
[Similar Products]
 NCBI Protein Information    probable E3 SUMO-protein ligase RNF212
 UniProt Protein Name    Probable E3 SUMO-protein ligase RNF212
 UniProt Synonym Protein Names   
RING finger protein 212
 Protein Family    RING finger protein
 UniProt Gene Name    RNF212 [Similar Products]
 UniProt Entry Name    RN212_HUMAN
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 NCBI Summary for RNF212    This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene may influence recombination rates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
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 UniProt Comments for RNF212    RNF212: SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination. 6 human isoforms produced by alternative splicing.

Protein type: EC 6.3.2.-; SUMO ligase; Ubiquitin conjugating system; Ligase

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: synaptonemal complex

Molecular Function: zinc ion binding; ligase activity

Biological Process: protein sumoylation; meiotic recombination; meiotic gene conversion; chiasma formation

Disease: Recombination Rate Quantitative Trait Locus 1
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 Research Articles on RNF212    1. This paper describes a partial transcript of the human RNF212 gene.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RNF212 antibodyOrgans/Tissues associated with anti-RNF212 antibody
 Reference Product  PubMed Publications
 MSH4 antibody  >2 publications with RNF212 and MSH4
 PRDM9 antibody  >2 publications with RNF212 and PRDM9
 KIAA1462 antibody  >1 publications with RNF212 and KIAA1462
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with RNF212 and Testis
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