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anti-SFTPD antibody :: Rabbit surfactant protein D Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS716873 anti-SFTPD antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

surfactant protein D (SFTPD), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human surfactant protein D polyclonal Antibody

 Product Synonym Names    surfactant protein D; SFTPD; COLEC7; PSP-D; SFTP4; SP-D
 Product Gene Name   

anti-SFTPD antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    178635
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Immunogen    Human SFTPD
 Conjugate    Non-conjugated
 Storage Buffer    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7709 / sc-7708 / sc-13980
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 Preparation and Storage    Shipped at 4degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SFTPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SFTPD antibody

   Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
 Applications Tested/Suitable for anti-SFTPD antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-SFTPD antibody    IP : 1:200-1:1000
IHC : 1:20-1:200 (Recommender dilution)
Positive IP detected in: Mouse lung tissue
Positive IHC detected in: Human lung cancer tissue, human kidney tissue, human placenta tissue
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NCBI/Uniprot data below describe general gene information for SFTPD. It may not necessarily be applicable to this product.
 NCBI GI #    292507
 NCBI GeneID    6441
 NCBI Accession #    AAB59450.1 [Other Products]
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 UniProt Secondary Accession #    Q5T0M3; Q6FH08; Q86YK9; Q8TCD8; Q9UCJ2; Q9UCJ3 [Other Products]
 UniProt Related Accession #    P35247 [Other Products]
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 NCBI Official Full Name    surfactant protein D
 NCBI Official Synonym Full Names    surfactant protein D
 NCBI Official Symbol    SFTPD [Similar Products]
 NCBI Official Synonym Symbols   
SP-D; PSP-D; SFTP4; COLEC7
[Similar Products]
 NCBI Protein Information    pulmonary surfactant-associated protein D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4
 UniProt Protein Name    Pulmonary surfactant-associated protein D
 UniProt Synonym Protein Names   
Collectin-7; Lung surfactant protein D
 Protein Family    Pulmonary surfactant-associated protein
 UniProt Gene Name    SFTPD [Similar Products]
 UniProt Synonym Gene Names    COLEC7; PSPD; SFTP4; PSP-D; SP-D [Similar Products]
 UniProt Entry Name    SFTPD_HUMAN
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 NCBI Summary for SFTPD    The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]
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 UniProt Comments for SFTPD    SFTPD: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q22.2-q23.1

Cellular Component: extracellular space; proteinaceous extracellular matrix; collagen; lysosome; endocytic vesicle; extracellular region

Molecular Function: protein binding; carbohydrate binding

Biological Process: receptor-mediated endocytosis; negative regulation of T cell proliferation; positive regulation of phagocytosis; negative regulation of interleukin-2 biosynthetic process; defense response to bacterium; innate immune response; respiratory gaseous exchange; macrophage chemotaxis; surfactant homeostasis; alveolus development; regulation of cytokine production
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 Research Articles on SFTPD    1. a novel pathway for the immunomodulatory functions of SP-D mediated via binding of its collagenous domains to LAIR-1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SFTPD antibodyPathways associated with anti-SFTPD antibody
 Reference Product  PubMed Publications
 SFTPB antibody  >7 publications with SFTPD and SFTPB
 SFTPC antibody  >5 publications with SFTPD and SFTPC
 TLR4 antibody  >2 publications with SFTPD and TLR4
 Products by Pathway  Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram
Diseases associated with anti-SFTPD antibodyOrgans/Tissues associated with anti-SFTPD antibody
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >23 publications with SFTPD and Lung Diseases
 Inflammation Antibodies  >15 publications with SFTPD and Inflammation
 Lung Injury Antibodies  >8 publications with SFTPD and Lung Injury
 Pneumonia Antibodies  >5 publications with SFTPD and Pneumonia
 Respiratory Hypersensitivity Antibodies  >3 publications with SFTPD and Respiratory Hypersensitivity
 Cardiovascular Diseases Antibodies  >3 publications with SFTPD and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >3 publications with SFTPD and Lung Neoplasms
 Respiratory Distress Syndrome, Adult Antibodies  >2 publications with SFTPD and Respiratory Distress Syndrome, Adult
 Disease Models, Animal Antibodies  >2 publications with SFTPD and Disease Models, Animal
 Necrosis Antibodies  >2 publications with SFTPD and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >33 publications with SFTPD and Lung
 Connective Tissue Antibodies  >2 publications with SFTPD and Connective Tissue
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