AAH13690.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Synaptotagmin XI
NCBI Official Synonym Full Names
synaptotagmin XI
NCBI Official Synonym Symbols
NCBI Protein Information
synaptotagmin-11; synaptotagmin 12
UniProt Protein Name
Synaptotagmin-11
UniProt Synonym Protein Names
Synaptotagmin XI; SytXI
UniProt Synonym Gene Names
UniProt Entry Name
SYT11_HUMAN
NCBI Summary for SYT11
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
UniProt Comments for SYT11
SYT11: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q21.2
Cellular Component: synaptic vesicle; synaptic vesicle membrane; integral to plasma membrane; cell junction
Molecular Function: protein binding; calcium-dependent phospholipid binding; transporter activity; calcium ion binding
Biological Process: transport; negative regulation of neurotransmitter secretion
Research Articles on SYT11
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Products associated with anti-SYT11 antibody
Pathways associated with anti-SYT11 antibody
Diseases associated with anti-SYT11 antibody
Organs/Tissues associated with anti-SYT11 antibody
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