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anti-TF antibody :: Rabbit transferrin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS710050 anti-TF antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

transferrin (TF), Polyclonal Antibody

 Also Known As   

Rabbit anti-human transferrin polyclonal Antibody

 Product Synonym Names    transferrin; TF; DKFZp781D0156; PRO1557; PRO2086
 Product Gene Name   

anti-TF antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 209300
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human TF
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22596 / sc-21011 / sc-30159
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-TF antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for TF. It may not necessarily be applicable to this product.
 NCBI GI #    339453
 NCBI GeneID    7018
 NCBI Accession #    AAA61140.1 [Other Products]
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 UniProt Secondary Accession #    O43890; Q1HBA5; Q9NQB8; Q9UHV0 [Other Products]
 UniProt Related Accession #    P02787 [Other Products]
 Molecular Weight    77,064 Da [Similar Products]
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 NCBI Official Full Name    transferrin
 NCBI Official Synonym Full Names    transferrin
 NCBI Official Symbol    TF [Similar Products]
 NCBI Official Synonym Symbols   
TFQTL1; PRO1557; PRO2086
[Similar Products]
 NCBI Protein Information    serotransferrin; siderophilin; beta-1 metal-binding globulin
 UniProt Protein Name    Serotransferrin
 UniProt Synonym Protein Names   
Beta-1 metal-binding globulin; Siderophilin
 Protein Family    Transferrin
 UniProt Gene Name    TF [Similar Products]
 UniProt Synonym Gene Names    Transferrin [Similar Products]
 UniProt Entry Name    TRFE_HUMAN
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 NCBI Summary for TF    This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
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 UniProt Comments for TF    TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: extracellular space; cell surface; early endosome; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; endocytic vesicle; perinuclear region of cytoplasm; apical plasma membrane; late endosome; basal plasma membrane; endosome membrane; vesicle

Molecular Function: protein binding; ferric iron binding; ubiquitin protein ligase binding

Biological Process: retinal homeostasis; platelet activation; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport

Disease: Atransferrinemia
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 Research Articles on TF    1. TF translocates to the cell front in association with cytoskeleton proteins and regulates HVSMC migration by mechanisms dependent and independent of factor (F)VIIa/PAR2
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TF antibodyPathways associated with anti-TF antibody
 Reference Product  PubMed Publications
 ALB antibody  >83 publications with TF and ALB
 HFE antibody  >74 publications with TF and HFE
 TFR2 antibody  >43 publications with TF and TFR2
 TFRC antibody  >22 publications with TF and TFRC
 TTR antibody  >7 publications with TF and TTR
 SLC40A1 antibody  >6 publications with TF and SLC40A1
 IGFBP3 antibody  >5 publications with TF and IGFBP3
 APOA1 antibody  >4 publications with TF and APOA1
 Products by Pathway  Pathway Diagram
 EPHB Forward Signaling Pathway antibodies  EPHB Forward Signaling Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Iron Metabolism In Placenta Pathway antibodies  Iron Metabolism In Placenta Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
Diseases associated with anti-TF antibodyOrgans/Tissues associated with anti-TF antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1460 publications with TF and Cardiovascular Diseases
 Inflammation Antibodies  >779 publications with TF and Inflammation
 Nervous System Diseases Antibodies  >668 publications with TF and Nervous System Diseases
 Carcinoma Antibodies  >519 publications with TF and Carcinoma
 Necrosis Antibodies  >498 publications with TF and Necrosis
 Immune System Diseases Antibodies  >425 publications with TF and Immune System Diseases
 Atherosclerosis Antibodies  >284 publications with TF and Atherosclerosis
 Liver Diseases Antibodies  >241 publications with TF and Liver Diseases
 Lung Neoplasms Antibodies  >172 publications with TF and Lung Neoplasms
 Anemia Antibodies  >143 publications with TF and Anemia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4608 publications with TF and Blood
 Brain Antibodies  >940 publications with TF and Brain
 Heart Antibodies  >680 publications with TF and Heart
 Liver Antibodies  >614 publications with TF and Liver
 Muscle Antibodies  >540 publications with TF and Muscle
 Lung Antibodies  >471 publications with TF and Lung
 Kidney Antibodies  >437 publications with TF and Kidney
 Embryonic Tissue Antibodies  >381 publications with TF and Embryonic Tissue
 Nerve Antibodies  >210 publications with TF and Nerve
 Skin Antibodies  >207 publications with TF and Skin
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