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anti-TMEM27 antibody :: Rabbit transmembrane protein 27 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711479 anti-TMEM27 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

transmembrane protein 27 (TMEM27), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human transmembrane protein 27 polyclonal Antibody

 Product Synonym Names    transmembrane protein 27; TMEM27; NX-17; NX17
 Product Gene Name   

anti-TMEM27 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300631
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human TMEM27
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-135464 / sc-135465
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TMEM27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-TMEM27 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for TMEM27. It may not necessarily be applicable to this product.
 NCBI GI #    119619300
 NCBI GeneID    57393
 NCBI Accession #    EAW98894.1 [Other Products]
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 UniProt Secondary Accession #    Q6UW07; B2R9M1 [Other Products]
 UniProt Related Accession #    Q9HBJ8 [Other Products]
 Molecular Weight    25,235 Da [Similar Products]
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 NCBI Official Full Name    transmembrane protein 27
 NCBI Official Synonym Full Names    transmembrane protein 27
 NCBI Official Symbol    TMEM27 [Similar Products]
 NCBI Official Synonym Symbols   
NX17; NX-17
[Similar Products]
 NCBI Protein Information    collectrin; kidney-specific membrane protein
 UniProt Protein Name    Collectrin
 UniProt Synonym Protein Names   
Transmembrane protein 27
 Protein Family    Collectrin
 UniProt Gene Name    TMEM27 [Similar Products]
 UniProt Entry Name    TMM27_HUMAN
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 NCBI Summary for TMEM27    This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
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 UniProt Comments for TMEM27    TMEM27: Regulator of SNARE complex function. Stimulator of beta cell replication. Belongs to the TMEM27 family.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: brush border membrane; cytoplasm; integral to membrane

Molecular Function: peptidyl-dipeptidase activity; protein binding; metallopeptidase activity

Biological Process: positive regulation of calcium ion-dependent exocytosis; proteolysis; positive regulation of amino acid transport
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 Research Articles on TMEM27    1. Bace2 specifically targets Tmem27 and cleaves its extracellular domain, which is then shed from the plasma membrane of pancreatic beta cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TMEM27 antibodyDiseases associated with anti-TMEM27 antibody
 Reference Product  PubMed Publications
 SLC6A19 antibody  >8 publications with TMEM27 and SLC6A19
 SNAPIN antibody  >3 publications with TMEM27 and SNAPIN
 SLC6A20 antibody  >1 publications with TMEM27 and SLC6A20
 SLC3A1 antibody  >1 publications with TMEM27 and SLC3A1
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >11 publications with TMEM27 and Kidney Diseases
 Brain Diseases Antibodies  >6 publications with TMEM27 and Brain Diseases
 Hypertension Antibodies  >5 publications with TMEM27 and Hypertension
 Heart Diseases Antibodies  >1 publications with TMEM27 and Heart Diseases
 Fibrosis Antibodies  >1 publications with TMEM27 and Fibrosis
 Liver Diseases Antibodies  >1 publications with TMEM27 and Liver Diseases
 Pancreatic Neoplasms Antibodies  >1 publications with TMEM27 and Pancreatic Neoplasms
 Inflammation Antibodies  >1 publications with TMEM27 and Inflammation
Organs/Tissues associated with anti-TMEM27 antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >26 publications with TMEM27 and Kidney
 Blood Antibodies  >8 publications with TMEM27 and Blood
 Lung Antibodies  >3 publications with TMEM27 and Lung
 Liver Antibodies  >2 publications with TMEM27 and Liver
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