Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow TRIM32 rightarrow Polyclonal TRIM32  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • fucosyltransferase 2 (secretor status included) (FUT2) ELISA Kit
 • Defensin Alpha 5, Paneth Cell Specific (DEFAlpha 5) ELISA Kit
 • Dyskerin (DKC1) Antibody
 • HBeAg Antibody
 • flotillin 1 (FLOT1) ELISA Kit
 • G antigen 12J (GAGE12J) Recombinant Protein
 • Secretory Leukocyte Peptidase Inhibitor (SLPI) Recombinant Protein
 • Cubilin (CUBN) Antibody
 • Bone Morphogenetic Protein 7 (BMP7) ELISA Kit
 • Activating Transcription Factor 2 (ATF2) ELISA Kit
 • GSK3B Antibody
 • Microtubule-Associated Protein Light Chain 3 (MAPLC3) ELISA Kit
 • CSNK2A2 Antibody
 • Endotoxin-Core Antibody IgM (EC-IgM) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-TRIM32 antibody :: Rabbit tripartite motif-containing 32 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714538 anti-TRIM32 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

tripartite motif-containing 32 (TRIM32), Polyclonal Antibody

 Also Known As   

Rabbit anti-human tripartite motif-containing 32 polyclonal Antibody

 Product Synonym Names    tripartite motif-containing 32; TRIM32; BBS11; HT2A; LGMD2H; TATIP
 Product Gene Name   

anti-TRIM32 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    602290
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Antigen Affinity Purified
Section Bar
 Immunogen    Human TRIM32
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49265 / sc-49266 / sc-134120 / sc-99011
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TRIM32 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-TRIM32 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TRIM32. It may not necessarily be applicable to this product.
 NCBI GI #    13111963
 NCBI GeneID    22954
 NCBI Accession #    AAH03154.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q9NQP8 [Other Products]
 UniProt Related Accession #    Q13049 [Other Products]
 Molecular Weight    71,989 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    Tripartite motif-containing 32
 NCBI Official Synonym Full Names    tripartite motif containing 32
 NCBI Official Symbol    TRIM32 [Similar Products]
 NCBI Official Synonym Symbols   
HT2A; BBS11; TATIP; LGMD2H
[Similar Products]
 NCBI Protein Information    E3 ubiquitin-protein ligase TRIM32; zinc finger protein HT2A; zinc-finger protein HT2A; 72 kDa Tat-interacting protein; TAT-interactive protein, 72-KD; tripartite motif-containing 32; tripartite motif-containing protein 32
 UniProt Protein Name    E3 ubiquitin-protein ligase TRIM32
 UniProt Synonym Protein Names   
72 kDa Tat-interacting protein; Tripartite motif-containing protein 32; Zinc finger protein HT2A
 Protein Family    E3 ubiquitin-protein ligase
 UniProt Gene Name    TRIM32 [Similar Products]
 UniProt Synonym Gene Names    HT2A [Similar Products]
 UniProt Entry Name    TRI32_HUMAN
Section Bar
 NCBI Summary for TRIM32    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for TRIM32    TRIM32: Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo. Defects in TRIM32 are the cause of limb-girdle muscular dystrophy type 2H (LGMD2H); also known as muscular dystrophy Hutterite type. LGMD2H is an autosomal recessive degenerative myopathy characterized by pelvic girdle, shoulder girdle and quadriceps muscle weakness. Clinical phenotype and severity are highly variable. Disease progression is slow and most patients remain ambulatory into the sixth decade of life. Defects in TRIM32 are the cause of Bardet-Biedl syndrome type 11 (BBS11). Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. A relatively high incidence of BBS is found in the mixed Arab populations of Kuwait and in Bedouin tribes throughout the Middle East, most likely due to the high rate of consaguinity in these populations and a founder effect. Belongs to the TRIM/RBCC family.

Protein type: Ubiquitin conjugating system; Ligase; EC 6.3.2.19; EC 6.3.2.-; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 9q33.1

Cellular Component: striated muscle thick filament; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; ubiquitin binding; myosin binding; protein self-association; zinc ion binding; RNA binding; translation initiation factor binding; Tat protein binding; transcription coactivator activity; ubiquitin-protein ligase activity; ligase activity

Biological Process: fat cell differentiation; regulation of interferon type I production; positive regulation of neurogenesis; protein polyubiquitination; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of proteolysis; protein ubiquitination during ubiquitin-dependent protein catabolic process; positive regulation of cell cycle; protein ubiquitination; positive regulation of cell growth; activation of NF-kappaB transcription factor; negative regulation of viral transcription; negative regulation of fibroblast proliferation; positive regulation of interferon type I production; positive regulation of protein catabolic process; innate immune response; positive regulation of transcription factor activity; positive regulation of neuron differentiation; positive regulation of cell migration; response to UV

Disease: Muscular Dystrophy, Limb-girdle, Type 2h; Bardet-biedl Syndrome 11
Table BarTOPTable Bar
 Research Articles on TRIM32    1. BBS11 promotes accumulation of NPHP7, changing the properties of NPHP7. TRIM32 Modulates the Transcriptional Activities of Glis2
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-TRIM32 antibodyPathways associated with anti-TRIM32 antibody
 Reference Product  PubMed Publications
 FKRP antibody  >5 publications with TRIM32 and FKRP
 MYC antibody  >5 publications with TRIM32 and MYC
 PIAS4 antibody  >4 publications with TRIM32 and PIAS4
 BBS10 antibody  >2 publications with TRIM32 and BBS10
 ABI2 antibody  >2 publications with TRIM32 and ABI2
 PIAS3 antibody  >1 publications with TRIM32 and PIAS3
 UBE2N antibody  >1 publications with TRIM32 and UBE2N
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies  Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cytosolic Sensors Of Pathogen-associated DNA Pathway antibodies  Cytosolic Sensors Of Pathogen-associated DNA Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Regulation Of Innate Immune Responses To Cytosolic DNA Pathway antibodies  Regulation Of Innate Immune Responses To Cytosolic DNA Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
Diseases associated with anti-TRIM32 antibodyOrgans/Tissues associated with anti-TRIM32 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >35 publications with TRIM32 and Nervous System Diseases
 Limb-girdle muscular dystrophy type 2H Antibodies  >18 publications with TRIM32 and Limb-girdle muscular dystrophy type 2H
 Bardet-Biedl Syndrome Antibodies  >12 publications with TRIM32 and Bardet-Biedl Syndrome
 Necrosis Antibodies  >4 publications with TRIM32 and Necrosis
 Cell Transformation, Neoplastic Antibodies  >3 publications with TRIM32 and Cell Transformation, Neoplastic
 Weight Loss Antibodies  >2 publications with TRIM32 and Weight Loss
 Disease Models, Animal Antibodies  >1 publications with TRIM32 and Disease Models, Animal
 Hypertrophy Antibodies  >1 publications with TRIM32 and Hypertrophy
 Kidney Diseases Antibodies  >1 publications with TRIM32 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >26 publications with TRIM32 and Muscle
 Brain Antibodies  >11 publications with TRIM32 and Brain
 Skin Antibodies  >4 publications with TRIM32 and Skin
 Kidney Antibodies  >3 publications with TRIM32 and Kidney
 Heart Antibodies  >1 publications with TRIM32 and Heart
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions