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anti-UQCRQ antibody :: Rabbit ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS710103 anti-UQCRQ antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa (UQCRQ), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa polyclonal Antibody

 Product Synonym Names    ubiquinol-cytochrome c reductase; complex III subunit VII; 9.5kDa; UQCRQ; QCR8; QP-C; QPC
 Product Gene Name   

anti-UQCRQ antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 615159
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human UQCRQ
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-74880
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-UQCRQ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-UQCRQ antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for UQCRQ. It may not necessarily be applicable to this product.
 NCBI GI #    12655079
 NCBI GeneID    27089
 NCBI Accession #    AAH01390.1 [Other Products]
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 UniProt Secondary Accession #    Q5FVE2; Q9BV88; Q9T2V7 [Other Products]
 UniProt Related Accession #    O14949 [Other Products]
 Molecular Weight    9,906 Da [Similar Products]
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 NCBI Official Full Name    Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
 NCBI Official Synonym Full Names    ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
 NCBI Official Symbol    UQCRQ [Similar Products]
 NCBI Official Synonym Symbols   
QPC; QCR8; QP-C; UQCR7; MC3DN4
[Similar Products]
 NCBI Protein Information    cytochrome b-c1 complex subunit 8; complex III subunit 8; complex III subunit VIII; low molecular mass ubiquinone-binding protein (9.5kD); ubiquinol-cytochrome c reductase complex 9.5 kDa protein; ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
 UniProt Protein Name    Cytochrome b-c1 complex subunit 8
 UniProt Synonym Protein Names   
Complex III subunit 8; Complex III subunit VIII; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
 UniProt Gene Name    UQCRQ [Similar Products]
 UniProt Entry Name    QCR8_HUMAN
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 NCBI Summary for UQCRQ    This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]
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 UniProt Comments for UQCRQ    UQCRQ: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone. Defects in UQCRQ are a cause of mitochondrial complex III deficiency (MT-C3D). A disorder of the mitochondrial respiratory chain resulting in a highly variable phenotype depending on which tissues are affected. Clinical features include mitochondrial encephalopathy, psychomotor retardation, ataxia, severe failure to thrive, liver dysfunction, renal tubulopathy, muscle weakness and exercise intolerance. Belongs to the UQCRQ/QCR8 family.

Protein type: Oxidoreductase; Mitochondrial; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: ubiquinol-cytochrome-c reductase activity

Biological Process: cellular metabolic process; hypothalamus development; pons development; hippocampus development; midbrain development; cerebellar Purkinje cell layer development; subthalamus development; pyramidal neuron development; thalamus development

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 4
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 Research Articles on UQCRQ    1. Decreased electron Transport Complex III activity is associated with ulcerative colitis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-UQCRQ antibodyPathways associated with anti-UQCRQ antibody
 Reference Product  PubMed Publications
 UQCRH antibody  >1 publications with UQCRQ and UQCRH
 COX7C antibody  >1 publications with UQCRQ and COX7C
 CYC1 antibody  >1 publications with UQCRQ and CYC1
 UQCR10 antibody  >1 publications with UQCRQ and UQCR10
 UQCRB antibody  >1 publications with UQCRQ and UQCRB
 UQCRC1 antibody  >1 publications with UQCRQ and UQCRC1
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cytochrome Bc1 Complex Pathway antibodies  Cytochrome Bc1 Complex Pathway Diagram
 Cytochrome Bc1 Complex Pathway antibodies  Cytochrome Bc1 Complex Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
Diseases associated with anti-UQCRQ antibodyOrgans/Tissues associated with anti-UQCRQ antibody
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >1 publications with UQCRQ and Mental Disorders
 Nervous System Diseases Antibodies  >1 publications with UQCRQ and Nervous System Diseases
 Mitochondrial Complex III Deficiency Antibodies  >1 publications with UQCRQ and Mitochondrial Complex III Deficiency
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >3 publications with UQCRQ and Muscle
 Blood Antibodies  >1 publications with UQCRQ and Blood
 Heart Antibodies  >1 publications with UQCRQ and Heart
 Brain Antibodies  >1 publications with UQCRQ and Brain
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