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anti-UPK2 antibody :: Rabbit uroplakin 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711806 anti-UPK2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

uroplakin 2 (UPK2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human uroplakin 2 polyclonal Antibody

 Product Synonym Names    uroplakin 2; UPK2; MGC138598; UP2; UPII
 Product Gene Name   

anti-UPK2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611558
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Immunogen    Human UPK2
 Conjugate    Non-conjugated
 Storage Buffer    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-15179 / sc-15178 / sc-15178
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-UPK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-UPK2 antibody

   Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM.
 Applications Tested/Suitable for anti-UPK2 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-UPK2 antibody    ELISA; Use at an assay dependent dilution.
WB : 1:200-1:2000
IHC : 1:20-1:200 (Recommender dilutions)
Positive WB detected in: Mouse testis tissue, mouse kidney tissue
Positive IHC detected in: Human bladder tissue
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NCBI/Uniprot data below describe general gene information for UPK2. It may not necessarily be applicable to this product.
 NCBI GI #    5803215
 NCBI GeneID    7379
 NCBI Accession #    NP_006751.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006760.3 [Other Products]
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 UniProt Secondary Accession #    O00457; Q53YV0; B0YJ92 [Other Products]
 UniProt Related Accession #    O00526 [Other Products]
 Molecular Weight    19,438 Da [Similar Products]
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 NCBI Official Full Name    uroplakin-2
 NCBI Official Synonym Full Names    uroplakin 2
 NCBI Official Symbol    UPK2 [Similar Products]
 NCBI Official Synonym Symbols   
UP2; UPII
[Similar Products]
 NCBI Protein Information    uroplakin-2; uroplakin II
 UniProt Protein Name    Uroplakin-2
 UniProt Synonym Protein Names   
Uroplakin II; UPII
 Protein Family    Uroplakin
 UniProt Gene Name    UPK2 [Similar Products]
 UniProt Synonym Gene Names    UP2; UPII [Similar Products]
 UniProt Entry Name    UPK2_HUMAN
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 NCBI Summary for UPK2    This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
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 UniProt Comments for UPK2    UPK2: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM. Belongs to the uroplakin-2 family.

Protein type: Membrane protein, integral; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: integral to plasma membrane; apical plasma membrane; integral to endoplasmic reticulum membrane

Biological Process: epithelial cell differentiation; multicellular organismal development
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 Research Articles on UPK2    1. Uroplakin II antibody BC21 demonstrated superior sensitivity and specificity in urothelial carcinoma, compared with uroplakin III, suggesting an advantage in differential diagnosis of urothelial carcinoma and in the detection of tumors of unknown origin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-UPK2 antibodyDiseases associated with anti-UPK2 antibody
 Reference Product  PubMed Publications
 UPK1A antibody  >29 publications with UPK2 and UPK1A
 UPK1B antibody  >28 publications with UPK2 and UPK1B
 KRT20 antibody  >7 publications with UPK2 and KRT20
 UPK3A antibody  >7 publications with UPK2 and UPK3A
 UPK3B antibody  >2 publications with UPK2 and UPK3B
 HMBS antibody  >1 publications with UPK2 and HMBS
 Disease Name  Pubmed Publications
 Urinary Bladder Neoplasms Antibodies  >37 publications with UPK2 and Urinary Bladder Neoplasms
 Carcinoma, Transitional Cell Antibodies  >25 publications with UPK2 and Carcinoma, Transitional Cell
 Cystitis Antibodies  >9 publications with UPK2 and Cystitis
 Hyperplasia Antibodies  >7 publications with UPK2 and Hyperplasia
 Neoplasms, Experimental Antibodies  >6 publications with UPK2 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >6 publications with UPK2 and Kidney Diseases
 Inflammation Antibodies  >6 publications with UPK2 and Inflammation
 Lung Neoplasms Antibodies  >5 publications with UPK2 and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >3 publications with UPK2 and Cell Transformation, Neoplastic
 Ovarian Neoplasms Antibodies  >3 publications with UPK2 and Ovarian Neoplasms
Organs/Tissues associated with anti-UPK2 antibody
 Organ/Tissue Name  Pubmed Publications
 Bladder Antibodies  >74 publications with UPK2 and Bladder
 Lung Antibodies  >7 publications with UPK2 and Lung
 Embryonic Tissue Antibodies  >5 publications with UPK2 and Embryonic Tissue
 Brain Antibodies  >4 publications with UPK2 and Brain
 Eye Antibodies  >3 publications with UPK2 and Eye
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