EAW77094.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma), isoform CRA_b
NCBI Official Synonym Full Names
v-akt murine thymoma viral oncogene homolog 3
NCBI Official Synonym Symbols
MPPH; PKBG; MPPH2; PRKBG; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma [Similar Products]
NCBI Protein Information
RAC-gamma serine/threonine-protein kinase; PKB gamma; RAC-gamma serine/threonine protein kinase; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
UniProt Protein Name
RAC-gamma serine/threonine-protein kinase
UniProt Synonym Protein Names
Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2
UniProt Synonym Gene Names
UniProt Entry Name
AKT3_HUMAN
NCBI Summary for AKT3
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for AKT3
Akt3: an AGC kinase that plays a critical role in controlling the balance between survival and apoptosis. Stimulated by platelet-derived growth factor, insulin, and insulin-like growth factor 1. Alternatively spliced isoforms have been described.
Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); AGC group; AKT family
Chromosomal Location of Human Ortholog: 1q44
Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; plasma membrane
Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase activity
Biological Process: mitochondrial genome maintenance; signal transduction; protein amino acid phosphorylation
Disease: Megalencephaly-polymicrogyria-polydactyly-hydrocephalus Syndrome 2
Research Articles on AKT3
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Products associated with anti-AKT3 antibody
Pathways associated with anti-AKT3 antibody
Diseases associated with anti-AKT3 antibody
Organs/Tissues associated with anti-AKT3 antibody
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