AAH48960.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
V-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
NCBI Official Synonym Full Names
YES proto-oncogene 1, Src family tyrosine kinase
NCBI Protein Information
tyrosine-protein kinase Yes; proto-oncogene c-Yes; cellular yes-1 protein; Yamaguchi sarcoma oncogene; proto-oncogene tyrosine-protein kinase YES; YES1 proto-oncogene, Src family tyrosine kinase; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
UniProt Protein Name
Tyrosine-protein kinase Yes
UniProt Synonym Protein Names
Proto-oncogene c-Yes; p61-Yes
UniProt Synonym Gene Names
UniProt Entry Name
YES_HUMAN
NCBI Summary for YES1
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
UniProt Comments for YES1
Yes: a proto-oncogenic cytosolic tyrosine kinase of the Src family. Expressed at high levels in adult neurons, spermatozoa, platelets, and epithelial cells.
Protein type: Oncoprotein; Protein kinase, TK; EC 2.7.10.2; Kinase, protein; Protein kinase, tyrosine (non-receptor); TK group; Src family
Chromosomal Location of Human Ortholog: 18p11.31-p11.21
Cellular Component: Golgi apparatus; extrinsic to internal side of plasma membrane; focal adhesion; cytoplasm; plasma membrane; microtubule organizing center; actin filament; cytosol
Molecular Function: protein binding; enzyme binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding; epidermal growth factor receptor binding
Biological Process: axon guidance; T cell costimulation; ephrin receptor signaling pathway; protein modification process; innate immune response; glucose transport; regulation of vascular permeability; blood coagulation; cell differentiation; leukocyte migration; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation
Research Articles on YES1
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Products associated with anti-YES1 antibody
Pathways associated with anti-YES1 antibody
Diseases associated with anti-YES1 antibody
Organs/Tissues associated with anti-YES1 antibody
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