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anti-ADCY1 antibody :: Rabbit anti-Human A Cyclase I Polycolonal Antibody

Scan QR to view Datasheet Catalog #    MBS9417675
Western Blot (WB)
Unit / Price
0.05 mL  /  $200 +1 FREE 8GB USB
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Cyclase I (ADCY1), Polycolonal Antibody

 Also Known As   

A Cyclase I Antibody

 Product Synonym Names    ADCY1; 3;5-cyclic AMP synthetase; Adenylate cyclase type I; AC1; Adenylate cyclase type 1; Adenylyl cyclase 1; ATP pyrophosphate-lyase 1; Adenyl cyclase; Adenylate cyclase 1 (brain); Adenylate cyclase; type i; ATP pyrophosphate-lyase
 Product Gene Name   

anti-ADCY1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AC069008 Genomic DNA
 3D Structure    ModBase 3D Structure for Q08828
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 Clonality    Polycolonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    A Cyclase I Antibody detects endogenous levels of total A Cyclase I
 Form/Format    Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1.0mg/mL (lot specific)
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 Immunogen    A synthesized peptide derived from human A Cyclase I
 Immunogen Type    Peptide
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 Preparation and Storage    Store at -20 degree C
 Other Notes    Small volumes of anti-ADCY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ADCY1 antibody    Total protein Ab
 Applications Tested/Suitable for anti-ADCY1 antibody   

Western Blot (WB)

 Application Notes for anti-ADCY1 antibody    Western Blot: 1:1000
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 Western Blot (WB) of anti-ADCY1 antibody    Western blot analysis A Cyclase I using COLO205 whole cell lysates
anti-ADCY1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ADCY1. It may not necessarily be applicable to this product.
 NCBI GI #    31083193
 NCBI GeneID    107
 NCBI Accession #    NP_066939.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021116.2 [Other Products]
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 UniProt Primary Accession #    Q08828 [Other Products]
 UniProt Secondary Accession #    Q75MI1; A4D2L8 [Other Products]
 UniProt Related Accession #    Q08828 [Other Products]
 Molecular Weight    123,440 Da [Similar Products]
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 NCBI Official Full Name    adenylate cyclase type 1 isoform 1
 NCBI Official Synonym Full Names    adenylate cyclase 1
 NCBI Official Symbol    ADCY1 [Similar Products]
 NCBI Official Synonym Symbols   
AC1; DFNB44
[Similar Products]
 NCBI Protein Information    adenylate cyclase type 1
 UniProt Protein Name    Adenylate cyclase type 1
 UniProt Synonym Protein Names   
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
 Protein Family    Adenylate cyclase
 UniProt Gene Name    ADCY1 [Similar Products]
 UniProt Entry Name    ADCY1_HUMAN
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 NCBI Summary for ADCY1    This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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 UniProt Comments for ADCY1    ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: cytoplasm; integral to plasma membrane; plasma membrane

Molecular Function: adenylate cyclase activity; calcium- and calmodulin-responsive adenylate cyclase activity

Biological Process: activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; regulation of circadian rhythm; renal water homeostasis

Disease: Deafness, Autosomal Recessive 44
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 Research Articles on ADCY1    1. Maps to 7p14.1-q11.22 between D7S2209 and marker D7S2435, maximum Lod score 5 for D7S1818.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ADCY1 antibodyDiseases associated with anti-ADCY1 antibody
 Products by Pathway  Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Adenylate Cyclase Activating Pathway antibodies  Adenylate Cyclase Activating Pathway Diagram
 Adenylate Cyclase Inhibitory Pathway antibodies  Adenylate Cyclase Inhibitory Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with ADCY1 and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with ADCY1 and Brain Diseases
 Depressive Disorder Antibodies  >2 publications with ADCY1 and Depressive Disorder
 Heart Diseases Antibodies  >1 publications with ADCY1 and Heart Diseases
 Disease Models, Animal Antibodies  >1 publications with ADCY1 and Disease Models, Animal
 Abnormalities, Drug-Induced Antibodies  >1 publications with ADCY1 and Abnormalities, Drug-Induced
 Adenocarcinoma Antibodies  >1 publications with ADCY1 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >1 publications with ADCY1 and Cell Transformation, Neoplastic
 Glucose Intolerance Antibodies  >1 publications with ADCY1 and Glucose Intolerance
Organs/Tissues associated with anti-ADCY1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with ADCY1 and Brain
 Eye Antibodies  >8 publications with ADCY1 and Eye
 Nerve Antibodies  >4 publications with ADCY1 and Nerve
 Embryonic Tissue Antibodies  >3 publications with ADCY1 and Embryonic Tissue
 Pancreas Antibodies  >2 publications with ADCY1 and Pancreas
 Kidney Antibodies  >2 publications with ADCY1 and Kidney
 Bone Antibodies  >1 publications with ADCY1 and Bone
 Skin Antibodies  >1 publications with ADCY1 and Skin
 Heart Antibodies  >1 publications with ADCY1 and Heart
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