NP_004065.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,579 Da
NCBI Official Full Name
cytochrome c oxidase subunit 8A, mitochondrial
NCBI Official Synonym Full Names
cytochrome c oxidase subunit 8A
NCBI Official Synonym Symbols
COX; COX8; VIII; COX8L; COX8-2; VIII-L [Similar Products]
NCBI Protein Information
cytochrome c oxidase subunit 8A, mitochondrial
UniProt Protein Name
Cytochrome c oxidase subunit 8A, mitochondrial
UniProt Synonym Protein Names
Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2
UniProt Synonym Gene Names
UniProt Entry Name
COX8A_HUMAN
NCBI Summary for COX82
The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]
UniProt Comments for COX82
COX8A: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIII family.
Protein type: Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Mitochondrial
Chromosomal Location of Human Ortholog: 11q12-q13
Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex IV
Molecular Function: protein binding
Biological Process: generation of precursor metabolites and energy; mitochondrial electron transport, cytochrome c to oxygen
Research Articles on COX82
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Pathways associated with anti-COX82 antibody
Diseases associated with anti-COX82 antibody
Organs/Tissues associated with anti-COX82 antibody
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