NP_001019818.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,021 Da
NCBI Official Full Name
rab-3A-interacting protein isoform A
NCBI Official Synonym Full Names
RAB3A interacting protein
NCBI Official Synonym Symbols
NCBI Protein Information
rab-3A-interacting protein; rabin-3; SSX2 interacting protein; SSX2-interacting protein; rab3A-interacting protein
UniProt Protein Name
Rab-3A-interacting protein
UniProt Synonym Protein Names
Rabin-3; SSX2-interacting protein
UniProt Synonym Gene Names
UniProt Entry Name
RAB3I_HUMAN
UniProt Comments for RAB3IP
RAB3IP: Guanine nucleotide exchange factor for RAB8A. Mediates the release of GDP from RAB8A but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Belongs to the SEC2 family. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rab
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: centrosome; cytoskeleton; lamellipodium; nucleus; cytosol
Molecular Function: protein binding; Rab guanyl-nucleotide exchange factor activity
Biological Process: Golgi to plasma membrane transport; protein localization in organelle; organelle organization and biogenesis; cilium biogenesis; protein targeting to membrane
Research Articles on RAB3IP
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Products associated with anti-RAB3IP antibody
Organs/Tissues associated with anti-RAB3IP antibody
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