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anti-RAB6A antibody :: Rabbit RAB6A Antibody

Scan QR to view Datasheet Catalog #    MBS003555 anti-RAB6A antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RAB6A, Antibody

 Also Known As   

Rabbit RAB6A Antibody

 Product Gene Name   

anti-RAB6A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 11; NC_000011.9 (73386683..73472201, complement). Location: 11q13.3
 OMIM    179513
 3D Structure    ModBase 3D Structure for P20340
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-RAB6A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RAB6A antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for RAB6A. It may not necessarily be applicable to this product.
 NCBI GI #    344030202
 NCBI GeneID    5870
 NCBI Accession #    NP_001230647.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243718.1 [Other Products]
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 UniProt Primary Accession #    P20340 [Other Products]
 UniProt Secondary Accession #    Q1W5D8; Q5U0A8; Q9UBE4; A8K133 [Other Products]
 UniProt Related Accession #    P20340 [Other Products]
 Molecular Weight    23,593 Da
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 NCBI Official Full Name    ras-related protein Rab-6A isoform d
 NCBI Official Synonym Full Names    RAB6A, member RAS oncogene family
 NCBI Official Symbol    RAB6A [Similar Products]
 NCBI Official Synonym Symbols   
RAB6
[Similar Products]
 NCBI Protein Information    ras-related protein Rab-6A; Rab GTPase; RAB6, member RAS oncogene family
 UniProt Protein Name    Ras-related protein Rab-6A
 Protein Family    Ras-related protein
 UniProt Gene Name    RAB6A [Similar Products]
 UniProt Synonym Gene Names    RAB6; Rab-6 [Similar Products]
 UniProt Entry Name    RAB6A_HUMAN
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 NCBI Summary for RAB6A    This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
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 UniProt Comments for RAB6A    RAB6A: Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Interacts with CCDC64; leads to its accumulation in the pericentrosomal region. Interacts with SCYL1BP1. Interacts with VSP52 and RABGAP1. Interacts with GCC2 (via its GRIP domain). Interacts with RAB6IP1 (via its RUN 1 domain). Isoform 1 interacts with RAB6KIFL. Isoform 2 does not interact with RAB6KIFL. Isoform 1 interacts with BICD1. Isoform 2 interacts with BICD1. Isoform 1 interacts with BICD2. Isoform 2 interacts with BICD2. Interacts with TMF1. Isoform 1 (GTP-bound) interacts with DYNLRB1; the interaction is direct. Isoform 2 (GDP-bound) interacts with DYNLRB1; the interaction is direct. Interacts with PIFO/C1orf88. Ubiquitous. Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: Golgi membrane; Golgi apparatus; membrane; trans-Golgi network; cytoplasmic vesicle; cytosol

Molecular Function: GTPase activity; protein domain specific binding; protein binding; GDP binding; GTP binding; myosin V binding

Biological Process: antigen processing and presentation; protein localization in Golgi apparatus; retrograde vesicle-mediated transport, Golgi to ER; peptidyl-cysteine methylation; protein targeting to Golgi; Rab protein signal transduction; retrograde transport, endosome to Golgi
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 Research Articles on RAB6A    1. Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RAB6A antibodyPathways associated with anti-RAB6A antibody
 Reference Product  PubMed Publications
 KIF20A antibody  >3 publications with RAB6A and KIF20A
 BICD2 antibody  >3 publications with RAB6A and BICD2
 BICD1 antibody  >2 publications with RAB6A and BICD1
 TMF1 antibody  >1 publications with RAB6A and TMF1
 SYTL5 antibody  >1 publications with RAB6A and SYTL5
 OCRL antibody  >1 publications with RAB6A and OCRL
 Products by Pathway  Pathway Diagram
 Pre-NOTCH Expression And Processing Pathway antibodies  Pre-NOTCH Expression And Processing Pathway Diagram
 Pre-NOTCH Processing In Golgi Pathway antibodies  Pre-NOTCH Processing In Golgi Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By NOTCH Pathway antibodies  Signaling By NOTCH Pathway Diagram
Diseases associated with anti-RAB6A antibodyOrgans/Tissues associated with anti-RAB6A antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with RAB6A and Neoplasms
 Brain Diseases Antibodies  >1 publications with RAB6A and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with RAB6A and Kidney Diseases
 Necrosis Antibodies  >1 publications with RAB6A and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with RAB6A and Brain
 Kidney Antibodies  >1 publications with RAB6A and Kidney
 Prostate Antibodies  >1 publications with RAB6A and Prostate
 Eye Antibodies  >1 publications with RAB6A and Eye
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