NP_006074.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
65,602 Da
NCBI Official Full Name
protein Red
NCBI Official Synonym Full Names
IK cytokine
NCBI Protein Information
protein Red
UniProt Protein Name
Protein Red
UniProt Synonym Protein Names
Cytokine IK
UniProt Synonym Gene Names
NCBI Summary for RED
The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. [provided by RefSeq, Jul 2008]
UniProt Comments for RED
Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166). Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mitotic cell cycle progression (PubMed:22351768, PubMed:24252166). Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint (PubMed:22351768). Required for normal accumulation of SMU1 (PubMed:24945353).
Product References and Citations for anti-RED antibody
Assier E., Gene 230:145-154(1999). Krief P., Oncogene 9:3449-3456(1994). Matsuoka S., Science 316:1160-1166(2007).
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Diseases associated with anti-RED antibody
Organs/Tissues associated with anti-RED antibody
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