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anti-RHG17 antibody :: Rabbit RHG17 Antibody

Scan QR to view Datasheet Catalog #    MBS002471 anti-RHG17 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RHG17, Antibody

 Also Known As   

Rabbit RHG17 Antibody

 Product Gene Name   

anti-RHG17 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 16; NC_000016.9 (24930710..25026675, complement). Location: 16p12.1
 OMIM    608293
 3D Structure    ModBase 3D Structure for Q68EM7
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-RHG17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RHG17 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for RHG17. It may not necessarily be applicable to this product.
 NCBI GI #    54860079
 NCBI GeneID    55114
 NCBI Accession #    NP_001006635.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001006634.1 [Other Products]
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 UniProt Primary Accession #    Q68EM7 [Other Products]
 UniProt Secondary Accession #    Q6ZUS4; Q7Z2F2; Q8NDG2; Q96KS2; Q96KS3; Q96SS8; Q9BVF6; Q9H8U5; Q9NW54; A8K6M6 [Other Products]
 UniProt Related Accession #    Q68EM7 [Other Products]
 Molecular Weight    95,437 Da
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 NCBI Official Full Name    rho GTPase-activating protein 17 isoform 1
 NCBI Official Synonym Full Names    Rho GTPase activating protein 17
 NCBI Official Symbol    ARHGAP17 [Similar Products]
 NCBI Official Synonym Symbols   
PP367; RICH1; WBP15; MST066; MST110; NADRIN; PP4534; RICH1B; MSTP038; MSTP066; MSTP110
[Similar Products]
 NCBI Protein Information    rho GTPase-activating protein 17; RICH-1; rho-type GTPase-activating protein 17; RhoGAP interacting with CIP4 homologs 1; rhoGAP interacting with CIP4 homologs protein 1; neuron-associated developmentally regulated protein
 UniProt Protein Name    Rho GTPase-activating protein 17
 UniProt Synonym Protein Names   
Rho-type GTPase-activating protein 17; RhoGAP interacting with CIP4 homologs protein 1
 UniProt Gene Name    ARHGAP17 [Similar Products]
 UniProt Synonym Gene Names    RICH1; RICH-1 [Similar Products]
 UniProt Entry Name    RHG17_HUMAN
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 NCBI Summary for RHG17    RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]
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 UniProt Comments for RHG17    ARHGAP17: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activitor in vitro for RAC1. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 16p12.1

Cellular Component: tight junction; plasma membrane; cytosol

Molecular Function: protein binding; SH3 domain binding; GTPase activator activity

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity
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 Research Articles on RHG17    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-RHG17 antibodyDiseases associated with anti-RHG17 antibody
 Products by Pathway  Pathway Diagram
 Regulation Of CDC42 Activity Pathway antibodies  Regulation Of CDC42 Activity Pathway Diagram
 Regulation Of RAC1 Activity Pathway antibodies  Regulation Of RAC1 Activity Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with RHG17 and Neoplasms
Organs/Tissues associated with anti-RHG17 antibody
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >3 publications with RHG17 and Nerve
 Brain Antibodies  >3 publications with RHG17 and Brain
 Embryonic Tissue Antibodies  >2 publications with RHG17 and Embryonic Tissue
 Blood Antibodies  >1 publications with RHG17 and Blood
 Spleen Antibodies  >1 publications with RHG17 and Spleen
 Kidney Antibodies  >1 publications with RHG17 and Kidney
 Lung Antibodies  >1 publications with RHG17 and Lung
 Placenta Antibodies  >1 publications with RHG17 and Placenta
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