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anti-RHOD antibody :: Rabbit anti-Human RHOD Antibody

Scan QR to view Datasheet Catalog #    MBS851638
Testing Data #2
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RHOD, Antibody

 Also Known As   

RHOD Antibody

 Product Synonym Names    Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1; RHOD
 Product Gene Name   

anti-RHOD antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605781
 3D Structure    ModBase 3D Structure for O00212
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 Host    Rabbit
 Species Reactivity    Human
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 Specificity    RHOD antibody detects endogenous levels of total RHOD protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Reactivity Note    Human (Identities = 100%, Positives = 100%)
 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human RHOD.
 Pathway    GTP-binding
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-RHOD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-RHOD antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-RHOD antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-RHOD antibody    WB: 1:500~1:1000, ELISA: 1:10000
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 Testing Data #2 of anti-RHOD antibody    Western blot analysis of extracts from COLO205 cells, K562 cells, Jurkat cells and A549 cells, using RHOD antibody.
anti-RHOD antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for RHOD. It may not necessarily be applicable to this product.
 NCBI GI #    7656900
 NCBI GeneID    29984
 NCBI Accession #    NP_055393.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_014578.3 [Other Products]
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 UniProt Primary Accession #    O00212 [Other Products]
 UniProt Related Accession #    O00212 [Other Products]
 Molecular Weight    23,413 Da
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 NCBI Official Full Name    rho-related GTP-binding protein RhoD isoform 1
 NCBI Official Synonym Full Names    ras homolog family member D
 NCBI Official Symbol    RHOD [Similar Products]
 NCBI Official Synonym Symbols   
Rho; ARHD; RHOM; RHOHP1
[Similar Products]
 NCBI Protein Information    rho-related GTP-binding protein RhoD; ras homolog D; Rho-related protein HP1; ras homolog gene family, member A; ras homolog gene family, member D
 UniProt Protein Name    Rho-related GTP-binding protein RhoD
 UniProt Synonym Protein Names   
Rho-related protein HP1; RhoHP1
 Protein Family    Rhodopsin
 UniProt Gene Name    RHOD [Similar Products]
 UniProt Synonym Gene Names    ARHD; RhoHP1 [Similar Products]
 UniProt Entry Name    RHOD_HUMAN
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 NCBI Summary for RHOD    Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
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 UniProt Comments for RHOD    RHOD: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein; Motility/polarity/chemotaxis; G protein, monomeric; G protein, monomeric, Rho

Chromosomal Location of Human Ortholog: 11q14.3

Cellular Component: early endosome; plasma membrane; cytosol

Molecular Function: GTPase activity; GTP binding; protein kinase binding

Biological Process: lamellipodium biogenesis; focal adhesion formation; actin filament bundle formation; regulation of small GTPase mediated signal transduction; positive regulation of cell adhesion; metabolic process; small GTPase mediated signal transduction; regulation of focal adhesion formation; Rho protein signal transduction; positive regulation of cell migration; protein targeting
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Product References and Citations for anti-RHOD antibody

   Shimizu F., Biochim. Biophys. Acta 1351:13-16(1997).
Puhl H.L. III, Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Taylor T.D., Nature 440:497-500(2006).
Gasman S., Nat. Cell Biol. 5:195-204(2003).
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 Research Articles on RHOD    1. Activated p42/44-MAP kinase, Rho GTPase.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RHOD antibodyPathways associated with anti-RHOD antibody
 Reference Product  PubMed Publications
 RAC2 antibody  >2 publications with RHOD and RAC2
 PLXNA1 antibody  >1 publications with RHOD and PLXNA1
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram
Diseases associated with anti-RHOD antibodyOrgans/Tissues associated with anti-RHOD antibody
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >42 publications with RHOD and Heart Diseases
 Necrosis Antibodies  >12 publications with RHOD and Necrosis
 Inflammation Antibodies  >7 publications with RHOD and Inflammation
 Kidney Diseases Antibodies  >4 publications with RHOD and Kidney Diseases
 Blood Coagulation Disorders Antibodies  >3 publications with RHOD and Blood Coagulation Disorders
 Pancreatic Neoplasms Antibodies  >3 publications with RHOD and Pancreatic Neoplasms
 Adenocarcinoma Antibodies  >3 publications with RHOD and Adenocarcinoma
 Hemorrhage Antibodies  >3 publications with RHOD and Hemorrhage
 Liver Diseases Antibodies  >3 publications with RHOD and Liver Diseases
 Drug-Induced Liver Injury Antibodies  >3 publications with RHOD and Drug-Induced Liver Injury
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >128 publications with RHOD and Muscle
 Heart Antibodies  >106 publications with RHOD and Heart
 Eye Antibodies  >22 publications with RHOD and Eye
 Kidney Antibodies  >13 publications with RHOD and Kidney
 Liver Antibodies  >11 publications with RHOD and Liver
 Pancreas Antibodies  >8 publications with RHOD and Pancreas
 Lung Antibodies  >7 publications with RHOD and Lung
 Intestine Antibodies  >7 publications with RHOD and Intestine
 Skin Antibodies  >6 publications with RHOD and Skin
 Embryonic Tissue Antibodies  >6 publications with RHOD and Embryonic Tissue
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