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anti-RNF14 antibody :: Rabbit RNF14 Antibody

Scan QR to view Datasheet Catalog #    MBS003807 anti-RNF14 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RNF14, Antibody

 Also Known As   

Rabbit RNF14 Antibody

 Product Gene Name   

anti-RNF14 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 5; NC_000005.9 (141346402..141369856). Location: 5q23.3-q31.1
 OMIM    605675
 3D Structure    ModBase 3D Structure for Q9UBS8
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-RNF14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RNF14 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for RNF14. It may not necessarily be applicable to this product.
 NCBI GI #    318067966
 NCBI GeneID    9604
 NCBI Accession #    NP_001188294.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001201365.1 [Other Products]
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 UniProt Primary Accession #    Q9UBS8 [Other Products]
 UniProt Secondary Accession #    O94793; Q6IBV0; A0AV26; A6NMR2; A8MTW5; B3KN72; B7ZLV2; D3DQE4 [Other Products]
 UniProt Related Accession #    Q9UBS8 [Other Products]
 Molecular Weight    53,837 Da
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 NCBI Official Full Name    E3 ubiquitin-protein ligase RNF14 isoform 1
 NCBI Official Synonym Full Names    ring finger protein 14
 NCBI Official Symbol    RNF14 [Similar Products]
 NCBI Official Synonym Symbols   
ARA54; HFB30; TRIAD2; HRIHFB2038
[Similar Products]
 NCBI Protein Information    E3 ubiquitin-protein ligase RNF14; androgen receptor associated protein 54; androgen receptor-associated protein 54
 UniProt Protein Name    E3 ubiquitin-protein ligase RNF14
 UniProt Synonym Protein Names   
Androgen receptor-associated protein 54; HFB30; RING finger protein 14; Triad2 protein
 Protein Family    E3 ubiquitin-protein ligase
 UniProt Gene Name    RNF14 [Similar Products]
 UniProt Synonym Gene Names    ARA54 [Similar Products]
 UniProt Entry Name    RNF14_HUMAN
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 NCBI Summary for RNF14    The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
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 UniProt Comments for RNF14    RNF14: Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. Belongs to the RBR family. RNF14 subfamily.

Protein type: Ubiquitin conjugating system; Nuclear receptor co-regulator; Ubiquitin ligase; EC 6.3.2.-; EC 6.3.2.19; Transcription, coactivator/corepressor; Ligase

Chromosomal Location of Human Ortholog: 5q23.3-q31.1

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; androgen receptor binding; small conjugating protein ligase activity; zinc ion binding; transcription coactivator activity; ligase activity

Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; androgen receptor signaling pathway; protein ubiquitination; signal transduction; response to estradiol stimulus
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 Research Articles on RNF14    1. Differential localization of ARA54 may play an important role in testicular development and spermatogenesis in humans.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RNF14 antibodyPathways associated with anti-RNF14 antibody
 Reference Product  PubMed Publications
 NCOA4 antibody  >11 publications with RNF14 and NCOA4
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
Diseases associated with anti-RNF14 antibodyOrgans/Tissues associated with anti-RNF14 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with RNF14 and Neoplasms
 Genital Diseases, Male Antibodies  >12 publications with RNF14 and Genital Diseases, Male
 Prostatic Diseases Antibodies  >11 publications with RNF14 and Prostatic Diseases
 Prostatic Neoplasms Antibodies  >11 publications with RNF14 and Prostatic Neoplasms
 Carcinoma Antibodies  >2 publications with RNF14 and Carcinoma
 Breast Neoplasms Antibodies  >1 publications with RNF14 and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with RNF14 and Cell Transformation, Neoplastic
 Necrosis Antibodies  >1 publications with RNF14 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >11 publications with RNF14 and Prostate
 Muscle Antibodies  >2 publications with RNF14 and Muscle
 Ovary Antibodies  >1 publications with RNF14 and Ovary
 Thyroid Antibodies  >1 publications with RNF14 and Thyroid
 Nerve Antibodies  >1 publications with RNF14 and Nerve
 Vascular Antibodies  >1 publications with RNF14 and Vascular
 Lymph Node Antibodies  >1 publications with RNF14 and Lymph Node
 Blood Antibodies  >1 publications with RNF14 and Blood
 Testis Antibodies  >1 publications with RNF14 and Testis
 Brain Antibodies  >1 publications with RNF14 and Brain
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