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anti-Rac1 antibody :: Rac1 Antibody

Scan QR to view Datasheet Catalog #    MBS8511721 anti-Rac1 antibody
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Rac1, Antibody

★Popular Item★
 Also Known As   

Rac1 Antibody

 Product Synonym Names    Ras-like protein TC25; Ras-related C3 botulinum toxin substrate 1; p21-Rac1
 Product Gene Name   

anti-Rac1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602048
 3D Structure    ModBase 3D Structure for P63000
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    Rac1 antibody detects endogenous levels of total Rac1
 Form/Format    In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    A synthesized peptide derived from human Rac1
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 Preparation and Storage    Store at-20 degree C for 1 year
 Other Notes    Small volumes of anti-Rac1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Rac1 antibody

   Rac1 encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
 Applications Tested/Suitable for anti-Rac1 antibody   

Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-Rac1 antibody    WB: 1:500~1:1000
IF: 1:200
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NCBI/Uniprot data below describe general gene information for Rac1. It may not necessarily be applicable to this product.
 NCBI GI #    9845511
 NCBI GeneID    5879
 NCBI Accession #    NP_008839.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006908.4 [Other Products]
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 UniProt Primary Accession #    P63000 [Other Products]
 UniProt Secondary Accession #    O95501; P15154; Q3Y4D3; Q5JAA8; Q9BTB4 [Other Products]
 UniProt Related Accession #    P63000 [Other Products]
 Molecular Weight    26 kd
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 NCBI Official Full Name    ras-related C3 botulinum toxin substrate 1 isoform Rac1
 NCBI Official Synonym Full Names    Rac family small GTPase 1
 NCBI Official Symbol    RAC1 [Similar Products]
 NCBI Official Synonym Symbols   
MIG5; MRD48; Rac-1; TC-25; p21-Rac1
[Similar Products]
 NCBI Protein Information    ras-related C3 botulinum toxin substrate 1
 UniProt Protein Name    Ras-related C3 botulinum toxin substrate 1
 UniProt Synonym Protein Names   
Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1
 Protein Family    Ras-related protein
 UniProt Gene Name    RAC1 [Similar Products]
 UniProt Synonym Gene Names    TC25 [Similar Products]
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 NCBI Summary for Rac1    The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for Rac1    Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In glioma cells, promotes cell migration and invasion. In podocytes, promotes nuclear shuttling of NR3C2; this modulation is required for a proper kidney functioning. Required for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. In synapses, seems to mediate the regulation of F-actin cluster formation performed by SHANK3.
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 Research Articles on Rac1    1. the pathological role of Rac1 signaling
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Rac1 antibodyPathways associated with anti-Rac1 antibody
 Reference Product  PubMed Publications
 PAK1 antibody  >256 publications with Rac1 and PAK1
 TIAM1 antibody  >151 publications with Rac1 and TIAM1
 VAV1 antibody  >101 publications with Rac1 and VAV1
 IQGAP1 antibody  >96 publications with Rac1 and IQGAP1
 AKT1 antibody  >57 publications with Rac1 and AKT1
 PAK2 antibody  >38 publications with Rac1 and PAK2
 ARHGDIA antibody  >30 publications with Rac1 and ARHGDIA
 DOCK1 antibody  >28 publications with Rac1 and DOCK1
 ARFIP2 antibody  >8 publications with Rac1 and ARFIP2
 NCF2 antibody  >3 publications with Rac1 and NCF2
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Activation Of Rac Pathway antibodies  Activation Of Rac Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
Diseases associated with anti-Rac1 antibodyOrgans/Tissues associated with anti-Rac1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >903 publications with Rac1 and Neoplasms
 Cardiovascular Diseases Antibodies  >252 publications with Rac1 and Cardiovascular Diseases
 Inflammation Antibodies  >225 publications with Rac1 and Inflammation
 Neoplasm Metastasis Antibodies  >179 publications with Rac1 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >167 publications with Rac1 and Disease Models, Animal
 Necrosis Antibodies  >148 publications with Rac1 and Necrosis
 Brain Diseases Antibodies  >142 publications with Rac1 and Brain Diseases
 Cell Transformation, Neoplastic Antibodies  >132 publications with Rac1 and Cell Transformation, Neoplastic
 Heart Diseases Antibodies  >117 publications with Rac1 and Heart Diseases
 Hypertension Antibodies  >101 publications with Rac1 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >800 publications with Rac1 and Blood
 Vascular Antibodies  >651 publications with Rac1 and Vascular
 Brain Antibodies  >483 publications with Rac1 and Brain
 Muscle Antibodies  >431 publications with Rac1 and Muscle
 Lung Antibodies  >285 publications with Rac1 and Lung
 Nerve Antibodies  >283 publications with Rac1 and Nerve
 Kidney Antibodies  >251 publications with Rac1 and Kidney
 Heart Antibodies  >247 publications with Rac1 and Heart
 Bone Antibodies  >188 publications with Rac1 and Bone
 Embryonic Tissue Antibodies  >155 publications with Rac1 and Embryonic Tissue
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