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anti-SDCBP antibody :: SDCBP Antibody

Scan QR to view Datasheet Catalog #    MBS8501272
Western Blot
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SDCBP, Antibody

★Popular Item★
 Also Known As   

SDCBP Antibody

 Product Gene Name   

anti-SDCBP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602217
 3D Structure    ModBase 3D Structure for O00560
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 Other Notes    Small volumes of anti-SDCBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Western Blot of anti-SDCBP antibody    Western blot analysis of extracts of various celllines, using SDCBP antibody.
anti-SDCBP antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for SDCBP. It may not necessarily be applicable to this product.
 NCBI GI #    55749490
 NCBI GeneID    6386
 NCBI Accession #    NP_001007068.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001007067.1 [Other Products]
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 UniProt Primary Accession #    O00560 [Other Products]
 UniProt Secondary Accession #    O00173; O43391; Q14CP2; B2R5Q7; B4DUH3; B7ZLN2 [Other Products]
 UniProt Related Accession #    O00560 [Other Products]
 Molecular Weight    31,762 Da
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 NCBI Official Full Name    syntenin-1 isoform 1
 NCBI Official Synonym Full Names    syndecan binding protein
 NCBI Official Symbol    SDCBP [Similar Products]
 NCBI Official Synonym Symbols   
ST1; MDA9; SYCL; MDA-9; TACIP18
[Similar Products]
 NCBI Protein Information    syntenin-1
 UniProt Protein Name    Syntenin-1
 UniProt Synonym Protein Names   
Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1
 Protein Family    Syntenin
 UniProt Gene Name    SDCBP [Similar Products]
 UniProt Synonym Gene Names    MDA9; SYCL; MDA-9; TACIP18 [Similar Products]
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 NCBI Summary for SDCBP    The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Jan 2017]
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 UniProt Comments for SDCBP    Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis (PubMed:26291527). Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1 (PubMed:25893292). In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis (PubMed:22660413). Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types (PubMed:26539120). In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) (PubMed:11498591). May also play a role in vesicular trafficking (PubMed:11179419). Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (PubMed:10230395).
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 Research Articles on SDCBP    1. These findings demonstrate that syntenin promotes VEGF signaling and, through its PDZ-dependent interaction with ephrin-B2, enhances VEGF-mediated VEGFR2 endocytosis and subsequent downstream signaling and angiogenesis in endothelial cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SDCBP antibodyPathways associated with anti-SDCBP antibody
 Reference Product  PubMed Publications
 SRC antibody  >13 publications with SDCBP and SRC
 SDC2 antibody  >4 publications with SDCBP and SDC2
 SOX4 antibody  >2 publications with SDCBP and SOX4
 CD6 antibody  >2 publications with SDCBP and CD6
 SDC4 antibody  >2 publications with SDCBP and SDC4
 IL5RA antibody  >2 publications with SDCBP and IL5RA
 STX1A antibody  >1 publications with SDCBP and STX1A
 NFASC antibody  >1 publications with SDCBP and NFASC
 SDC1 antibody  >1 publications with SDCBP and SDC1
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 Ephrin Signaling Pathway antibodies  Ephrin Signaling Pathway Diagram
 IL-5 Signaling Pathway antibodies  IL-5 Signaling Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
 Neurofascin Interactions Pathway antibodies  Neurofascin Interactions Pathway Diagram
 Syndecan-1-mediated Signaling Events Pathway antibodies  Syndecan-1-mediated Signaling Events Pathway Diagram
 Syndecan-2-mediated Signaling Events Pathway antibodies  Syndecan-2-mediated Signaling Events Pathway Diagram
 Syndecan-4-mediated Signaling Events Pathway antibodies  Syndecan-4-mediated Signaling Events Pathway Diagram
Diseases associated with anti-SDCBP antibodyOrgans/Tissues associated with anti-SDCBP antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with SDCBP and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >3 publications with SDCBP and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >3 publications with SDCBP and Disease Models, Animal
 Brain Diseases Antibodies  >3 publications with SDCBP and Brain Diseases
 Carcinoma Antibodies  >2 publications with SDCBP and Carcinoma
 Kidney Diseases Antibodies  >2 publications with SDCBP and Kidney Diseases
 Lung Neoplasms Antibodies  >1 publications with SDCBP and Lung Neoplasms
 Liver Neoplasms Antibodies  >1 publications with SDCBP and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with SDCBP and Liver Diseases
 Prostatic Diseases Antibodies  >1 publications with SDCBP and Prostatic Diseases
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >12 publications with SDCBP and Nerve
 Brain Antibodies  >11 publications with SDCBP and Brain
 Blood Antibodies  >10 publications with SDCBP and Blood
 Embryonic Tissue Antibodies  >5 publications with SDCBP and Embryonic Tissue
 Vascular Antibodies  >5 publications with SDCBP and Vascular
 Kidney Antibodies  >5 publications with SDCBP and Kidney
 Muscle Antibodies  >4 publications with SDCBP and Muscle
 Stomach Antibodies  >3 publications with SDCBP and Stomach
 Liver Antibodies  >3 publications with SDCBP and Liver
 Lung Antibodies  >3 publications with SDCBP and Lung
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