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anti-SGK269 antibody :: Rabbit anti-Human SGK269 Antibody

Scan QR to view Datasheet Catalog #    MBS003611 anti-SGK269 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SGK269, Antibody

 Also Known As   

Rabbit SGK269 Antibody

 Product Gene Name   

anti-SGK269 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 15; NC_000015.9 (77400498..77712446, complement). Location: 15q24.3
 OMIM    614248
 3D Structure    ModBase 3D Structure for Q9H792
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 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-SGK269 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-SGK269 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for SGK269. It may not necessarily be applicable to this product.
 NCBI GI #    148368962
 NCBI GeneID    79834
 NCBI Accession #    NP_079052.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_024776.3 [Other Products]
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 UniProt Primary Accession #    Q9H792 [Other Products]
 UniProt Secondary Accession #    Q6ZS78; Q8NAZ4; Q8NCM3; Q8TEG7 [Other Products]
 UniProt Related Accession #    Q9H792 [Other Products]
 Molecular Weight    193,106 Da
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 NCBI Official Full Name    pseudopodium-enriched atypical kinase 1
 NCBI Official Symbol    PEAK1 [Similar Products]
 NCBI Official Synonym Symbols   
SGK269
[Similar Products]
 NCBI Protein Information    pseudopodium-enriched atypical kinase 1; sugen kinase 269; tyrosine-protein kinase SgK269; pseudopodium enriched atypical kinase
 UniProt Protein Name    Pseudopodium-enriched atypical kinase 1
 UniProt Synonym Protein Names   
Sugen kinase 269; Tyrosine-protein kinase SgK269
 UniProt Gene Name    PEAK1 [Similar Products]
 UniProt Synonym Gene Names    KIAA2002 [Similar Products]
 UniProt Entry Name    PEAK1_HUMAN
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 NCBI Summary for SGK269    This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014]
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 UniProt Comments for SGK269    PEAK1: Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN. Belongs to the protein kinase superfamily.

Protein type: Protein kinase, Other; Kinase, protein; EC 2.7.10.2; Protein kinase, Ser/Thr (non-receptor); Other group; NKF3 family

Chromosomal Location of Human Ortholog: 15q24.3

Cellular Component: nucleoplasm; focal adhesion; cytoplasm; plasma membrane; actin cytoskeleton

Molecular Function: protein binding; non-membrane spanning protein tyrosine kinase activity; ATP binding

Biological Process: cell migration; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation
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 Research Articles on SGK269    1. phosphorylation of tyrosine 665 in pseudopodium-enriched atypical kinase 1 (PEAK1) is essential for the regulation of cell migration and focal adhesion turnover
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-SGK269 antibodyOrgans/Tissues associated with anti-SGK269 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with SGK269 and Neoplasms
 Scleroderma, Diffuse Antibodies  >1 publications with SGK269 and Scleroderma, Diffuse
 Liver Neoplasms Antibodies  >1 publications with SGK269 and Liver Neoplasms
 Lymphoma Antibodies  >1 publications with SGK269 and Lymphoma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with SGK269 and Blood
 Liver Antibodies  >1 publications with SGK269 and Liver
 Muscle Antibodies  >1 publications with SGK269 and Muscle
 Brain Antibodies  >1 publications with SGK269 and Brain
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