NP_003054.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
~6 kDa observed. An uncharacterized band may be observed at ~13kDa in some tissue lysates.
NCBI Official Full Name
sarcolipin
NCBI Official Synonym Full Names
sarcolipin
NCBI Protein Information
sarcolipin
UniProt Protein Name
Sarcolipin
NCBI Summary for SLN
Sarcoplasmic reticulum Ca(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca(2+)-ATPases. The transmembrane protein interacts with Ca(2+)-ATPases and reduces the accumulation of Ca(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008]
UniProt Comments for SLN
Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis ().
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Products associated with anti-SLN antibody
Pathways associated with anti-SLN antibody
Diseases associated with anti-SLN antibody
Organs/Tissues associated with anti-SLN antibody
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