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anti-SMN antibody :: Rabbit anti-Human SMN (Survival of motor neuron) Antibody

Scan QR to view Datasheet Catalog #    MBS462130
Testing Data
Unit / Price
0.1 mg  /  $285 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SMN (Survival of motor neuron), Antibody

 Also Known As   

Rabbit anti SMN antibody

 Product Synonym Names    Rabbit anti-SMN; Survival of motor neuron; Gemin1; SMA
 Product Gene Name   

anti-SMN antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Host    Rabbit
 Species Reactivity    Human
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 Specificity    This antibody recognizes ~35 kDa of human SMN protein. The other species are not tested
 Purity/Purification    The Rabbit IgG is purified by Epitope Affinity Purification.
 Form/Format    This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
 Concentration    Size: 100 ug/200 ul (lot specific)
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 Antigen Preparation    A synthetic peptide corresponding to C-terminus of human SMN.
 Positive Control    Hela cell lysate
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 Preparation and Storage    The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
 Other Notes    Small volumes of anti-SMN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SMN antibody

   The survival motor neuron (SMN) protein is the protein product of the spinal muscular atrophy (SMA) disease. SMN gene is the SMA determining gene. In humans, there are two nearly identical copies of the survival of motor neuron genes (SMN1 and SMN2), whereas other eukaryotic species have only one copy of the SMN gene. SMN is expressed ubiquitously and is a core component of a self-assembling multiprotein complex. The SMN complex, consisting of SMN and Gemin proteins (Gemin2, -3, -4, -5, -6, -7 and -8), in which SMN-Gemin2 complex plays an essential role in the assembly and regeneration of small nuclear ribonucleoproteins (snRNPs) and spliceosomes.
 Applications Tested/Suitable for anti-SMN antibody   

ELISA, Western Blot, Immunohistochemistry

 Application Notes for anti-SMN antibody    Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
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 Testing Data of anti-SMN antibody    anti-SMN antibody Testing Data image
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 Molecular Weight    35 kDa
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Product References and Citations for anti-SMN antibody

   Ogawa C, et al. Gemin2 Plays an Important Role in Stabilizing the Survival of Motor Neuron Complex.J. Biol. Chem., Vol 282 (15)11122-11134 (2007).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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