NP_004773.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
28,970 Da
NCBI Official Full Name
synaptosomal-associated protein 29
NCBI Official Synonym Full Names
synaptosome associated protein 29
NCBI Protein Information
synaptosomal-associated protein 29
UniProt Protein Name
Synaptosomal-associated protein 29
UniProt Synonym Protein Names
Soluble 29 kDa NSF attachment protein
UniProt Synonym Gene Names
NCBI Summary for SNAP29
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SNAP29
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions.
Research Articles on SNAP29
Precautions
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Products associated with anti-SNAP29 antibody
Pathways associated with anti-SNAP29 antibody
Diseases associated with anti-SNAP29 antibody
Organs/Tissues associated with anti-SNAP29 antibody
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