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anti-SOD1 antibody :: Mouse anti-Human, Mouse SOD1 Antibody

Scan QR to view Datasheet Catalog #    MBS850323
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SOD1, Antibody

★Popular Item★
 Also Known As   

SOD1 Antibody

 Product Synonym Names    ALS; SOD; ALS1; IPOA; homodimer
 Product Gene Name   

anti-SOD1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    105400
 3D Structure    ModBase 3D Structure for P00441
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 Isotype    IgG1
 Clone Number    6F5
 Host    Mouse
 Species Reactivity    Human, Mouse
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 Form/Format    Ascitic fluid containing 0.03% sodium azide.
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 Immunogen    Purified recombinant fragment of human SOD1 expressed in E. Coli.
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 Preparation and Storage    Store at 4 degree C, for long term storage, store at-20 degree C
 Other Notes    Small volumes of anti-SOD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SOD1 antibody

   SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.
 Product Categories/Family for anti-SOD1 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-SOD1 antibody   

Western Blot (WB), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA)

 Application Notes for anti-SOD1 antibody    WB: 1:500-1:2000
IF: 1:200-1:1000
FC: 1:200-1:400
ELISA: 1:10000
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 Western Blot (WB) of anti-SOD1 antibody    Figure 1. Western blot analysis using SOD1 mouse mAb against Hela (1), NIH/3T3 (2), A549 (3) and A431 (4) cell lysate.
anti-SOD1 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-SOD1 antibody    Figure 2. Confocal immunofluorescence analysis of PANC-1 (left) and SKBR-3 (right) cells using SOD1 mouse mAb (green). Red. Actin filaments have been labeled with DY-554 phalloidin. Blue. DRAQ5 fluorescent DNA dye.
anti-SOD1 antibody Immunofluorescence (IF) image
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 Immunofluorescence (IF) of anti-SOD1 antibody    Figure 3. Confocal immunofluorescence analysis of 3T3-L1 cells using SOD1 mouse mAb (green). Blue. DRAQ5 fluorescent DNA dye.
anti-SOD1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for SOD1. It may not necessarily be applicable to this product.
 NCBI GI #    4507149
 NCBI GeneID    6647
 NCBI Accession #    NP_000445.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000454.4 [Other Products]
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 UniProt Primary Accession #    P00441 [Other Products]
 UniProt Secondary Accession #    Q16669; Q16711; Q16838; Q16839; Q16840; Q6NR85; A6NHJ0; D3DSE4 [Other Products]
 UniProt Related Accession #    P00441 [Other Products]
 Molecular Weight    18kDa
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 NCBI Official Full Name    superoxide dismutase
 NCBI Official Synonym Full Names    superoxide dismutase 1
 NCBI Official Symbol    SOD1 [Similar Products]
 NCBI Official Synonym Symbols   
ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer
[Similar Products]
 NCBI Protein Information    superoxide dismutase [Cu-Zn]
 UniProt Protein Name    Superoxide dismutase [Cu-Zn]
 UniProt Synonym Protein Names   
Superoxide dismutase 1; hSod1
 Protein Family    Superoxide dismutase
 UniProt Gene Name    SOD1 [Similar Products]
 UniProt Synonym Gene Names    hSod1 [Similar Products]
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 NCBI Summary for SOD1    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SOD1    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
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 Research Articles on SOD1    1. Data provide evidence that metal binding, in addition of being necessary for SOD1 enzymatic activity, is a key factor in the aggregation process of SOD1. In particular, both demetalation and aberrant metal binding have been shown to promote misfolding and aggregation in SOD1 suggesting a possible role of metal binding in SOD1 pathological aggregation. [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SOD1 antibodyPathways associated with anti-SOD1 antibody
 Reference Product  PubMed Publications
 SOD2 antibody  >412 publications with SOD1 and SOD2
 CAT antibody  >198 publications with SOD1 and CAT
 CCS antibody  >98 publications with SOD1 and CCS
 BCL2 antibody  >23 publications with SOD1 and BCL2
 RNF19A antibody  >4 publications with SOD1 and RNF19A
 UBC antibody  >3 publications with SOD1 and UBC
 DNAJB1 antibody  >1 publications with SOD1 and DNAJB1
 ESR1 antibody  >1 publications with SOD1 and ESR1
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Dopamine Metabolism Pathway antibodies  Dopamine Metabolism Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with anti-SOD1 antibodyOrgans/Tissues associated with anti-SOD1 antibody
 Disease Name  Pubmed Publications
 Amyotrophic Lateral Sclerosis Antibodies  >2499 publications with SOD1 and Amyotrophic Lateral Sclerosis
 Nervous System Diseases Antibodies  >2466 publications with SOD1 and Nervous System Diseases
 Motor Neuron Disease Antibodies  >2246 publications with SOD1 and Motor Neuron Disease
 Disease Models, Animal Antibodies  >1060 publications with SOD1 and Disease Models, Animal
 Nerve Degeneration Antibodies  >313 publications with SOD1 and Nerve Degeneration
 Protein Deficiency Antibodies  >177 publications with SOD1 and Protein Deficiency
 Inflammation Antibodies  >172 publications with SOD1 and Inflammation
 Ischemia Antibodies  >139 publications with SOD1 and Ischemia
 Necrosis Antibodies  >114 publications with SOD1 and Necrosis
 Brain Ischemia Antibodies  >82 publications with SOD1 and Brain Ischemia
 Organ/Tissue Name  Pubmed Publications
 Spinal Cord Antibodies  >1102 publications with SOD1 and Spinal Cord
 Brain Antibodies  >940 publications with SOD1 and Brain
 Nerve Antibodies  >572 publications with SOD1 and Nerve
 Muscle Antibodies  >512 publications with SOD1 and Muscle
 Blood Antibodies  >456 publications with SOD1 and Blood
 Liver Antibodies  >182 publications with SOD1 and Liver
 Vascular Antibodies  >173 publications with SOD1 and Vascular
 Heart Antibodies  >90 publications with SOD1 and Heart
 Kidney Antibodies  >89 publications with SOD1 and Kidney
 Bone Antibodies  >76 publications with SOD1 and Bone
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