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anti-SSXT antibody :: Rabbit SSXT Antibody

Scan QR to view Datasheet Catalog #    MBS852193
Testing Data
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SSXT, Antibody

 Also Known As   

SSXT Antibody

 Product Synonym Names    SSXT protein; Synovial sarcoma; translocated to X chromosome; SYT protein; SS18; SSXT; SYT
 Product Gene Name   

anti-SSXT antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600192
 3D Structure    ModBase 3D Structure for Q15532
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 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    SSXT antibody detects endogenous levels of total SSXT protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from N-terminal of human SSXT.
 Pathway    Transcription
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-SSXT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-SSXT antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-SSXT antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-SSXT antibody    WB: 1:500~1:1000, ELISA: 1:1000
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 Testing Data of anti-SSXT antibody    Western blot analysis of extracts from HepG2 cells, COLO205 cells and Jurkat cells, using SSXT antibody.
anti-SSXT antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for SSXT. It may not necessarily be applicable to this product.
 NCBI GI #    56117846
 NCBI GeneID    6760
 NCBI Accession #    NP_001007560.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001007559.1 [Other Products]
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 UniProt Primary Accession #    Q15532 [Other Products]
 UniProt Secondary Accession #    Q16404; Q4VAX1; Q9BXC6; B0YJ95 [Other Products]
 UniProt Related Accession #    Q15532 [Other Products]
 Molecular Weight    42,216 Da
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 NCBI Official Full Name    protein SSXT isoform 1
 NCBI Official Synonym Full Names    synovial sarcoma translocation, chromosome 18
 NCBI Official Symbol    SS18 [Similar Products]
 NCBI Official Synonym Symbols   
SYT; SSXT
[Similar Products]
 NCBI Protein Information    protein SSXT; synovial sarcoma, translocated to X chromosome; synovial sarcoma translocated to X chromosome protein
 UniProt Protein Name    Protein SSXT
 UniProt Synonym Protein Names   
Protein SYT; Synovial sarcoma translocated to X chromosome protein
 UniProt Gene Name    SS18 [Similar Products]
 UniProt Synonym Gene Names    SSXT; SYT [Similar Products]
 UniProt Entry Name    SSXT_HUMAN
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 UniProt Comments for SSXT    SS18: Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). Belongs to the SS18 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator; Oncoprotein

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: cytoplasmic microtubule; nucleus

Molecular Function: protein binding; ligand-dependent nuclear receptor transcription coactivator activity

Biological Process: response to drug; transcription, DNA-dependent; cell morphogenesis; ephrin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; microtubule cytoskeleton organization and biogenesis
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Product References and Citations for anti-SSXT antibody

   Clark J., Nat. Genet. 7:502-508(1994).
Brodin B., Gene 268:173-182(2001).
Fligman I., Am. J. Pathol. 147:1592-1599(1995).
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 Research Articles on SSXT    1. SYT gene split is associated with Synovial sarcoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SSXT antibodyPathways associated with anti-SSXT antibody
 Reference Product  PubMed Publications
 SSX1 antibody  >64 publications with SSXT and SSX1
 SSX4 antibody  >13 publications with SSXT and SSX4
 SMARCA4 antibody  >3 publications with SSXT and SMARCA4
 SMARCA2 antibody  >3 publications with SSXT and SMARCA2
 COAA antibody  >1 publications with SSXT and COAA
 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with anti-SSXT antibodyOrgans/Tissues associated with anti-SSXT antibody
 Disease Name  Pubmed Publications
 Sarcoma, Synovial Antibodies  >127 publications with SSXT and Sarcoma, Synovial
 Neoplasm Metastasis Antibodies  >8 publications with SSXT and Neoplasm Metastasis
 Death Antibodies  >4 publications with SSXT and Death
 Kidney Diseases Antibodies  >4 publications with SSXT and Kidney Diseases
 Liver Diseases Antibodies  >3 publications with SSXT and Liver Diseases
 Embryo Loss Antibodies  >3 publications with SSXT and Embryo Loss
 Disease Models, Animal Antibodies  >2 publications with SSXT and Disease Models, Animal
 Brain Diseases Antibodies  >2 publications with SSXT and Brain Diseases
 Necrosis Antibodies  >2 publications with SSXT and Necrosis
 Congenital Abnormalities Antibodies  >1 publications with SSXT and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >14 publications with SSXT and Lung
 Bone Antibodies  >8 publications with SSXT and Bone
 Nerve Antibodies  >8 publications with SSXT and Nerve
 Kidney Antibodies  >7 publications with SSXT and Kidney
 Muscle Antibodies  >6 publications with SSXT and Muscle
 Heart Antibodies  >5 publications with SSXT and Heart
 Thyroid Antibodies  >4 publications with SSXT and Thyroid
 Liver Antibodies  >4 publications with SSXT and Liver
 Vascular Antibodies  >4 publications with SSXT and Vascular
 Testis Antibodies  >3 publications with SSXT and Testis
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