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anti-ST6GAL1 antibody :: Rabbit ST6GAL1 Antibody

Scan QR to view Datasheet Catalog #    MBS853436
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ST6GAL1, Antibody

 Also Known As   

ST6GAL1 Antibody

 Product Synonym Names    Alpha 2; 6-ST; B-cell antigen CD75; Beta-galactoside alpha-2; 6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2; 6-sialyltransferase; EC 2.4.99.1; SIA1; Sialyltransferase 1; ST6Gal I; ST6GAL1
 Product Gene Name   

anti-ST6GAL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    109675
 3D Structure    ModBase 3D Structure for P15907
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 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    ST6GAL1 antibody detects endogenous levels of total ST6GAL1 protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Reactivity Note    Human (Identities = 100%, Positives = 100%); Mouse (Identities = 92%, Positives = 100%); Rat (Identities = 92%, Positives = 100%)
 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human ST6GAL1.
 Pathway    Lymphocyte Signaling
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-ST6GAL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ST6GAL1 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-ST6GAL1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-ST6GAL1 antibody    WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:40000
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 Testing Data of anti-ST6GAL1 antibody    anti-ST6GAL1 antibody Testing Data image
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 Testing Data #2 of anti-ST6GAL1 antibody    Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using ST6GAL1 antibody.
Western blot analysis of extracts from RAW264.7 cells, using ST6GAL1 antibody.
anti-ST6GAL1 antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for ST6GAL1. It may not necessarily be applicable to this product.
 NCBI GI #    4506949
 NCBI GeneID    6480
 NCBI Accession #    NP_003023.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003032.2 [Other Products]
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 UniProt Primary Accession #    P15907 [Other Products]
 UniProt Secondary Accession #    A8KA14; B2R513; D3DNV3 [Other Products]
 UniProt Related Accession #    P15907 [Other Products]
 Molecular Weight    20,764 Da
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 NCBI Official Full Name    beta-galactoside alpha-2,6-sialyltransferase 1 isoform a
 NCBI Official Synonym Full Names    ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 NCBI Official Symbol    ST6GAL1 [Similar Products]
 NCBI Official Synonym Symbols   
ST6N; SIAT1; ST6GalI
[Similar Products]
 NCBI Protein Information    beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal I; alpha 2,6-ST 1; B-cell antigen CD75; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1
 UniProt Protein Name    Beta-galactoside alpha-2,6-sialyltransferase 1
 UniProt Synonym Protein Names   
B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1
 Protein Family    Beta-galactoside alpha-2,6-sialyltransferase
 UniProt Gene Name    ST6GAL1 [Similar Products]
 UniProt Synonym Gene Names    SIAT1; Alpha 2,6-ST 1; ST6GalI [Similar Products]
 UniProt Entry Name    SIAT1_HUMAN
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 NCBI Summary for ST6GAL1    This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009]
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 UniProt Comments for ST6GAL1    SIAT1: a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. Is normally found in the trans cisternae of the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found.

Protein type: EC 2.4.99.1; Transferase; Membrane protein, integral; Glycan Metabolism - N-glycan biosynthesis

Chromosomal Location of Human Ortholog: 3q27.3

Cellular Component: Golgi membrane; integral to Golgi membrane

Molecular Function: sialyltransferase activity; beta-galactoside alpha-2,6-sialyltransferase activity

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; O-glycan processing; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; humoral immune response; N-acetylneuraminate metabolic process
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Product References and Citations for anti-ST6GAL1 antibody

   Grundmann U.G., Nucleic Acids Res. 18:667-667(1990).
Stamenkovic I., J. Exp. Med. 172:641-643(1990).
Ota T., Nat. Genet. 36:40-45(2004).
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 Research Articles on ST6GAL1    1. ST6GAL1 is responsible for the development of multidrug resistance in human leukemia cells probably through medicating the activity of PI3K/Akt signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ST6GAL1 antibodyPathways associated with anti-ST6GAL1 antibody
 Reference Product  PubMed Publications
 B4GALT1 antibody  >3 publications with ST6GAL1 and B4GALT1
 MUC7 antibody  >1 publications with ST6GAL1 and MUC7
 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway antibodies  Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 N-Glycan Antennae Elongation Pathway antibodies  N-Glycan Antennae Elongation Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway antibodies  N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway Diagram
 N-glycan Biosynthesis, Complex Type Pathway antibodies  N-glycan Biosynthesis, Complex Type Pathway Diagram
 N-glycan Biosynthesis, Complex Type Pathway antibodies  N-glycan Biosynthesis, Complex Type Pathway Diagram
Diseases associated with anti-ST6GAL1 antibodyOrgans/Tissues associated with anti-ST6GAL1 antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >11 publications with ST6GAL1 and Liver Diseases
 Liver Neoplasms Antibodies  >8 publications with ST6GAL1 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with ST6GAL1 and Carcinoma, Hepatocellular
 Inflammation Antibodies  >5 publications with ST6GAL1 and Inflammation
 Cell Transformation, Neoplastic Antibodies  >3 publications with ST6GAL1 and Cell Transformation, Neoplastic
 Breast Neoplasms Antibodies  >3 publications with ST6GAL1 and Breast Neoplasms
 Diabetes Mellitus, Type 2 Antibodies  >3 publications with ST6GAL1 and Diabetes Mellitus, Type 2
 Hyperplasia Antibodies  >2 publications with ST6GAL1 and Hyperplasia
 Disease Models, Animal Antibodies  >2 publications with ST6GAL1 and Disease Models, Animal
 Kidney Diseases Antibodies  >2 publications with ST6GAL1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >32 publications with ST6GAL1 and Blood
 Liver Antibodies  >15 publications with ST6GAL1 and Liver
 Lymph Antibodies  >9 publications with ST6GAL1 and Lymph
 Lymph Node Antibodies  >9 publications with ST6GAL1 and Lymph Node
 Lung Antibodies  >7 publications with ST6GAL1 and Lung
 Vascular Antibodies  >6 publications with ST6GAL1 and Vascular
 Stomach Antibodies  >6 publications with ST6GAL1 and Stomach
 Bone Antibodies  >5 publications with ST6GAL1 and Bone
 Brain Antibodies  >5 publications with ST6GAL1 and Brain
 Skin Antibodies  >4 publications with ST6GAL1 and Skin
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