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anti-TNF14 antibody :: Rabbit anti-Human, mouse TNF14 Antibody

Scan QR to view Datasheet Catalog #    MBS000113 anti-TNF14 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TNF14, Antibody

 Also Known As   

Rabbit TNF14 Antibody

 Product Gene Name   

anti-TNF14 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000019.9 (6663148..6670599, complement). Location: 19p13.3
 OMIM    604520
 3D Structure    ModBase 3D Structure for O43557
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-TNF14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-TNF14 antibody   

Immunofluorescence (IF), ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for TNF14. It may not necessarily be applicable to this product.
 NCBI GI #    25952144
 NCBI GeneID    8740
 NCBI Accession #    NP_003798.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003807.3 [Other Products]
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 UniProt Primary Accession #    O43557 [Other Products]
 UniProt Secondary Accession #    O75476; Q6FHA1; Q8WVF8; Q96LD2; A8K7M2; C9J5H4 [Other Products]
 UniProt Related Accession #    O43557 [Other Products]
 Molecular Weight    26,350 Da
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 NCBI Official Full Name    tumor necrosis factor ligand superfamily member 14 isoform 1
 NCBI Official Synonym Full Names    tumor necrosis factor (ligand) superfamily, member 14
 NCBI Official Symbol    TNFSF14 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    tumor necrosis factor ligand superfamily member 14; delta transmembrane LIGHT; herpesvirus entry mediator A; herpesvirus entry mediator ligand; herpesvirus entry mediator-ligand; herpes virus entry mediator ligand; ligand for herpesvirus entry mediator; tumor necrosis factor receptor-like 2; tumor necrosis factor superfamily member LIGHT
 UniProt Protein Name    Tumor necrosis factor ligand superfamily member 14
 UniProt Synonym Protein Names   
Herpes virus entry mediator ligand
 UniProt Gene Name    TNFSF14 [Similar Products]
 UniProt Synonym Gene Names    HVEML; LIGHT; HVEM-L [Similar Products]
 UniProt Entry Name    TNF14_HUMAN
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 NCBI Summary for TNF14    The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNF14    TNFSF14: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cytokine; Inhibitor

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular space; cytoplasm; plasma membrane; integral to membrane

Molecular Function: protein binding; caspase inhibitor activity; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: release of cytoplasmic sequestered NF-kappaB; T cell proliferation; T cell activation; apoptosis; T cell costimulation; T cell homeostasis; immune response; negative regulation of caspase activity; signal transduction; positive regulation of myoblast differentiation
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 Research Articles on TNF14    1. findings show that LIGHT is not inhibited by the soluble RANKL receptor OPG and that LIGHT is a potent osteoclastogenesis factor that activates the Akt, NFkappaB and JNK pathways
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TNF14 antibodyPathways associated with anti-TNF14 antibody
 Reference Product  PubMed Publications
 TNFRSF14 antibody  >60 publications with TNF14 and TNFRSF14
 LTBR antibody  >37 publications with TNF14 and LTBR
 TNFRSF6B antibody  >14 publications with TNF14 and TNFRSF6B
 LTB antibody  >10 publications with TNF14 and LTB
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
Diseases associated with anti-TNF14 antibodyOrgans/Tissues associated with anti-TNF14 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >196 publications with TNF14 and Necrosis
 Inflammation Antibodies  >50 publications with TNF14 and Inflammation
 Neoplasms Antibodies  >39 publications with TNF14 and Neoplasms
 Disease Models, Animal Antibodies  >18 publications with TNF14 and Disease Models, Animal
 Liver Diseases Antibodies  >13 publications with TNF14 and Liver Diseases
 Neoplasms, Experimental Antibodies  >10 publications with TNF14 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >10 publications with TNF14 and Cardiovascular Diseases
 Arthritis, Rheumatoid Antibodies  >9 publications with TNF14 and Arthritis, Rheumatoid
 Brain Diseases Antibodies  >5 publications with TNF14 and Brain Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with TNF14 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >20 publications with TNF14 and Spleen
 Liver Antibodies  >15 publications with TNF14 and Liver
 Brain Antibodies  >6 publications with TNF14 and Brain
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