NP_003831.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,823 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 10D
NCBI Official Synonym Full Names
TNF receptor superfamily member 10d
NCBI Official Synonym Symbols
DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4 [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 10D
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 10D
UniProt Synonym Protein Names
Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain; CD_antigen: CD264
UniProt Synonym Gene Names
NCBI Summary for TNFRSF10D
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]
UniProt Comments for TNFRSF10D
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Product References and Citations for anti-TNFRSF10D antibody
Marsters S.A., Curr. Biol. 7:1003-1006(1997). Degli-Esposti M.A., Immunity 7:813-820(1997). Pan G., FEBS Lett. 424:41-45(1998).
Research Articles on TNFRSF10D
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Products associated with anti-TNFRSF10D antibody
Pathways associated with anti-TNFRSF10D antibody
Diseases associated with anti-TNFRSF10D antibody
Organs/Tissues associated with anti-TNFRSF10D antibody
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