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anti-TSPAN8 antibody :: Rabbit anti-Human TSPAN8 Antibody

Scan QR to view Datasheet Catalog #    MBS854885
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TSPAN8, Antibody

 Also Known As   

TSPAN8 Antibody

 Product Synonym Names    Tetraspanin-8; Tspan-8; Transmembrane 4 superfamily member 3; Tumor-associated antigen CO-029; TSPAN8; TM4SF3
 Product Gene Name   

anti-TSPAN8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600769
 3D Structure    ModBase 3D Structure for P19075
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 Host    Rabbit
 Species Reactivity    Human
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 Specificity    TSPAN8 antibody detects endogenous levels of total TSPAN8 protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human TSPAN8.
 Pathway    Lymphocyte Signaling
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-TSPAN8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-TSPAN8 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-TSPAN8 antibody   

Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-TSPAN8 antibody    WB: 1:500~1:1000, IF: 1:100~1:500, ELISA: 1:20000
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 Testing Data of anti-TSPAN8 antibody    anti-TSPAN8 antibody Testing Data image
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 Testing Data #2 of anti-TSPAN8 antibody    Peptide - +
Western blot analysis of extracts from 293 cells and COLO cells, using TSPAN8 antibody.
Immunofluorescence analysis of HeLa cells, using TSPAN8 antibody.
anti-TSPAN8 antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for TSPAN8. It may not necessarily be applicable to this product.
 NCBI GI #    4759238
 NCBI GeneID    7103
 NCBI Accession #    NP_004607.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004616.2 [Other Products]
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 UniProt Primary Accession #    P19075 [Other Products]
 UniProt Secondary Accession #    Q9BS78; B2R7T7 [Other Products]
 UniProt Related Accession #    P19075 [Other Products]
 Molecular Weight    26,044 Da
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 NCBI Official Full Name    tetraspanin-8
 NCBI Official Synonym Full Names    tetraspanin 8
 NCBI Official Symbol    TSPAN8 [Similar Products]
 NCBI Official Synonym Symbols   
CO-029; TM4SF3
[Similar Products]
 NCBI Protein Information    tetraspanin-8; tspan-8; tumor-associated antigen CO-029; transmembrane 4 superfamily member 3
 UniProt Protein Name    Tetraspanin-8
 UniProt Synonym Protein Names   
Transmembrane 4 superfamily member 3; Tumor-associated antigen CO-029
 UniProt Gene Name    TSPAN8 [Similar Products]
 UniProt Synonym Gene Names    TM4SF3; Tspan-8 [Similar Products]
 UniProt Entry Name    TSN8_HUMAN
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 NCBI Summary for TSPAN8    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TSPAN8    TSPAN8: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q14.1-q21.1

Cellular Component: integral to membrane

Biological Process: negative regulation of blood coagulation
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Product References and Citations for anti-TSPAN8 antibody

   Szala S., Proc. Natl. Acad. Sci. U.S.A. 87:6833-6837(1990).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
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 Research Articles on TSPAN8    1. CO-029 functions as a regulator of both cell-matrix and cell-cell adhesion. During colon cancer progression, CO-029 promotes cancer cell movement by deregulating cell adhesions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TSPAN8 antibodyDiseases associated with anti-TSPAN8 antibody
 Reference Product  PubMed Publications
 JAZF1 antibody  >22 publications with TSPAN8 and JAZF1
 THADA antibody  >21 publications with TSPAN8 and THADA
 ADAMTS9 antibody  >18 publications with TSPAN8 and ADAMTS9
 CDC123 antibody  >16 publications with TSPAN8 and CDC123
 CAMK1D antibody  >15 publications with TSPAN8 and CAMK1D
 CDKAL1 antibody  >12 publications with TSPAN8 and CDKAL1
 IGF2BP2 antibody  >12 publications with TSPAN8 and IGF2BP2
 SLC30A8 antibody  >10 publications with TSPAN8 and SLC30A8
 EPCAM antibody  >6 publications with TSPAN8 and EPCAM
 IRGM antibody  >1 publications with TSPAN8 and IRGM
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >16 publications with TSPAN8 and Carcinoma
 Neoplasm Metastasis Antibodies  >14 publications with TSPAN8 and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >12 publications with TSPAN8 and Adenocarcinoma
 Liver Diseases Antibodies  >6 publications with TSPAN8 and Liver Diseases
 Liver Neoplasms Antibodies  >5 publications with TSPAN8 and Liver Neoplasms
 Lung Neoplasms Antibodies  >4 publications with TSPAN8 and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >4 publications with TSPAN8 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >3 publications with TSPAN8 and Neoplasms, Experimental
 Carcinoma, Hepatocellular Antibodies  >3 publications with TSPAN8 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >2 publications with TSPAN8 and Kidney Diseases
Organs/Tissues associated with anti-TSPAN8 antibody
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >14 publications with TSPAN8 and Pancreas
 Liver Antibodies  >9 publications with TSPAN8 and Liver
 Vascular Antibodies  >7 publications with TSPAN8 and Vascular
 Lung Antibodies  >5 publications with TSPAN8 and Lung
 Connective Tissue Antibodies  >3 publications with TSPAN8 and Connective Tissue
 Brain Antibodies  >2 publications with TSPAN8 and Brain
 Muscle Antibodies  >2 publications with TSPAN8 and Muscle
 Heart Antibodies  >2 publications with TSPAN8 and Heart
 Kidney Antibodies  >2 publications with TSPAN8 and Kidney
 Bone Antibodies  >2 publications with TSPAN8 and Bone
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