NP_001020374.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,715 Da
NCBI Official Full Name
splicing factor U2AF 35 kDa subunit isoform b
NCBI Official Synonym Full Names
U2 small nuclear RNA auxiliary factor 1
NCBI Official Synonym Symbols
RN; FP793; U2AF35; U2AFBP; RNU2AF1 [Similar Products]
NCBI Protein Information
splicing factor U2AF 35 kDa subunit
UniProt Protein Name
Splicing factor U2AF 35 kDa subunit
UniProt Synonym Protein Names
U2 auxiliary factor 35 kDa subunit; U2 small nuclear RNA auxiliary factor 1; U2 snRNP auxiliary factor small subunit
UniProt Synonym Gene Names
NCBI Summary for U2AF1
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for U2AF1
Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Research Articles on U2AF1
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Products associated with anti-U2AF1 antibody
Pathways associated with anti-U2AF1 antibody
Diseases associated with anti-U2AF1 antibody
Organs/Tissues associated with anti-U2AF1 antibody
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