Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow UBE2D2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Glycoprotein V, Platelet (GP5) ELISA Kit
 • Hexarelin Native Protein
 • Macrophage Colony-Stimulating Factor Receptor (M-CSFR) ELISA Kit
 • Cross-Linked C-Terminal Telopeptides of Type II Collagen (CT... ELISA Kit
 • Influenza Viruses A Antibody IgG (FLUA-IgG) ELISA Kit
 • Apolipoprotein B (Apo B) (APOBEC4) Antibody
 • IL-17 (IL17A) Antibody
 • Abeta40 (Amyloid Beta 40) (Ab40) CLIA Kit
 • Gamma-secretase-activating protein (Pion) ELISA Kit
 • CD3- Antibody
 • AFGF-FGF1 ELISA Kit
 • 3 Carboxyl 4 Methyl 5 Propyl 2 Furangroup (CMPF) ELISA Kit
 • CRFR1 - CRHR1 Antibody
 • VEGF Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-UBE2D2 antibody :: UBE2D2 Antibody

Scan QR to view Datasheet Catalog #    MBS855125
Western Blot (WB)
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UBE2D2, Antibody

★Popular Item★
 Also Known As   

UBE2D2 Antibody

 Product Synonym Names    Ubiquitin-conjugating enzyme E2 D2; Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase D2; UBE2D2; UBC4; UBC5B; UBCH4; UBCH5B
 Product Gene Name   

anti-UBE2D2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    602962
 3D Structure    ModBase 3D Structure for P62837
Section Bar
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Specificity    UBE2D2 antibody detects endogenous levels of total UBE2D2 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Section Bar
 Immunogen    The antiserum was produced against synthesized peptide derived from C-terminal of human UBE2D2.
Section Bar
 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-UBE2D2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-UBE2D2 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-UBE2D2 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-UBE2D2 antibody    WB: 1:500~1:1000
ELISA: 1:40000
Section Bar
 Western Blot (WB) of anti-UBE2D2 antibody    Western blot analysis of extracts from HeLa cells, A549 cells and K562 cells, using UBE2D2 antibody.
anti-UBE2D2 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for UBE2D2. It may not necessarily be applicable to this product.
 NCBI GI #    4507775
 NCBI GeneID    7322
 NCBI Accession #    NP_003330.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003339.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P62837 [Other Products]
 UniProt Secondary Accession #    P51669; Q3MN78; Q96RP6; D3DQC9 [Other Products]
 UniProt Related Accession #    P62837 [Other Products]
 Molecular Weight    13,635 Da
Table BarTOPTable Bar
 NCBI Official Full Name    ubiquitin-conjugating enzyme E2 D2 isoform 1
 NCBI Official Synonym Full Names    ubiquitin conjugating enzyme E2 D2
 NCBI Official Symbol    UBE2D2 [Similar Products]
 NCBI Official Synonym Symbols   
UBC4; PUBC1; UBCH4; UBC4/5; UBCH5B; E2(17)KB2
[Similar Products]
 NCBI Protein Information    ubiquitin-conjugating enzyme E2 D2
 UniProt Protein Name    Ubiquitin-conjugating enzyme E2 D2
 UniProt Synonym Protein Names   
(E3-independent) E2 ubiquitin-conjugating enzyme D2 (EC:2.3.2.24
 Protein Family    Ubiquitin-conjugating enzyme
 UniProt Gene Name    UBE2D2 [Similar Products]
 UniProt Synonym Gene Names    PUBC1; UBC4; UBC5B; UBCH4; UBCH5B [Similar Products]
Section Bar
 NCBI Summary for UBE2D2    Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Section Bar
 UniProt Comments for UBE2D2    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
Table BarTOPTable Bar
 

Product References and Citations for anti-UBE2D2 antibody

   Jensen J.P., J. Biol. Chem. 270:30408-30414(1995). Rolfe M., Proc. Natl. Acad. Sci. U.S.A. 92:3264-3268(1995). Guinn B.-A., Biochem. Biophys. Res. Commun. 335:1293-1304(2005).
Section Bar
 Research Articles on UBE2D2    1. These results point to an important role of the affinity between RNF4 and its cognate RAD6B or UBCH5B in governing the multiplicity of substrate ubiquitination.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-UBE2D2 antibodyPathways associated with anti-UBE2D2 antibody
 Reference Product  PubMed Publications
 CBL antibody  >3 publications with UBE2D2 and CBL
 CNOT4 antibody  >2 publications with UBE2D2 and CNOT4
 NEDD4 antibody  >1 publications with UBE2D2 and NEDD4
 AMFR antibody  >1 publications with UBE2D2 and AMFR
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies  Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
 Cellular Response To Hypoxia Pathway antibodies  Cellular Response To Hypoxia Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 IKK Complex Recruitment Mediated By RIP1 Pathway antibodies  IKK Complex Recruitment Mediated By RIP1 Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
Diseases associated with anti-UBE2D2 antibodyOrgans/Tissues associated with anti-UBE2D2 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with UBE2D2 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >2 publications with UBE2D2 and Cardiovascular Diseases
 Memory Disorders Antibodies  >1 publications with UBE2D2 and Memory Disorders
 Disease Models, Animal Antibodies  >1 publications with UBE2D2 and Disease Models, Animal
 Learning Disorders Antibodies  >1 publications with UBE2D2 and Learning Disorders
 Brain Diseases Antibodies  >1 publications with UBE2D2 and Brain Diseases
 Drug Toxicity Antibodies  >1 publications with UBE2D2 and Drug Toxicity
 Inflammation Antibodies  >1 publications with UBE2D2 and Inflammation
 Necrosis Antibodies  >1 publications with UBE2D2 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with UBE2D2 and Brain
 Blood Antibodies  >3 publications with UBE2D2 and Blood
 Placenta Antibodies  >3 publications with UBE2D2 and Placenta
 Testis Antibodies  >2 publications with UBE2D2 and Testis
 Liver Antibodies  >1 publications with UBE2D2 and Liver
 Kidney Antibodies  >1 publications with UBE2D2 and Kidney
 Intestine Antibodies  >1 publications with UBE2D2 and Intestine
 Thymus Antibodies  >1 publications with UBE2D2 and Thymus
 Lung Antibodies  >1 publications with UBE2D2 and Lung
 Nerve Antibodies  >1 publications with UBE2D2 and Nerve
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions