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anti-VPS16 antibody :: VPS16 Antibody

Scan QR to view Datasheet Catalog #    MBS8506008 anti-VPS16 antibody
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

VPS16, Antibody

★Popular Item★
 Also Known As   

VPS16 Antibody

 Product Gene Name   

anti-VPS16 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608550
 3D Structure    ModBase 3D Structure for Q9H269
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 Other Notes    Small volumes of anti-VPS16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for VPS16. It may not necessarily be applicable to this product.
 NCBI GI #    17978479
 NCBI GeneID    64601
 NCBI Accession #    NP_072097.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022575.3 [Other Products]
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 UniProt Primary Accession #    Q9H269 [Other Products]
 UniProt Secondary Accession #    Q5JUB1; Q8WU31; Q96EE7; Q96N92; Q9H1Q4; Q9H1Q5 [Other Products]
 UniProt Related Accession #    Q9H269 [Other Products]
 Molecular Weight    78,300 Da
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 NCBI Official Full Name    vacuolar protein sorting-associated protein 16 homolog isoform 1
 NCBI Official Synonym Full Names    VPS16, CORVET/HOPS core subunit
 NCBI Official Symbol    VPS16 [Similar Products]
 NCBI Official Synonym Symbols   
hVPS16
[Similar Products]
 NCBI Protein Information    vacuolar protein sorting-associated protein 16 homolog
 UniProt Protein Name    Vacuolar protein sorting-associated protein 16 homolog
 Protein Family    Vacuolar protein sorting-associated protein
 UniProt Gene Name    VPS16 [Similar Products]
 UniProt Synonym Gene Names    hVPS16 [Similar Products]
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 NCBI Summary for VPS16    Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
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 UniProt Comments for VPS16    Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for recruitment of VPS33A to the HOPS complex (PubMed:23901104). Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS33A but not VPS33B (PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG (PubMed:24554770).
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 Research Articles on VPS16    1. VPS16 is a new causative gene for adolescent-onset primary dystonia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-VPS16 antibodyOrgans/Tissues associated with anti-VPS16 antibody
 Reference Product  PubMed Publications
 VPS18 antibody  >10 publications with VPS16 and VPS18
 VPS11 antibody  >8 publications with VPS16 and VPS11
 VPS41 antibody  >5 publications with VPS16 and VPS41
 VPS33A antibody  >3 publications with VPS16 and VPS33A
 VPS39 antibody  >3 publications with VPS16 and VPS39
 VPS8 antibody  >2 publications with VPS16 and VPS8
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with VPS16 and Nerve
 Skin Antibodies  >1 publications with VPS16 and Skin
 Eye Antibodies  >1 publications with VPS16 and Eye
 Brain Antibodies  >1 publications with VPS16 and Brain
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