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anti-c-Jun antibody :: c-Jun Antibody

Scan QR to view Datasheet Catalog #    MBS855302
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

c-Jun, Antibody

★Popular Item★
 Also Known As   

c-Jun (Ab-243) Antibody

 Product Gene Name   

anti-c-Jun antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    165160
 3D Structure    ModBase 3D Structure for P05412
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    c-Jun (Ab-243) antibody detects endogenous levels of total c-Jun protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of serine 243.
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 Preparation and Storage    Store at-20 degree C for 1 year
 Other Notes    Small volumes of anti-c-Jun antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-c-Jun antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-c-Jun antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA), Immunoprecipitation (IP)

 Application Notes for anti-c-Jun antibody    WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:20000
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 Immunohistochemistry (IHC) of anti-c-Jun antibody    Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Jun (Ab-243) antibody.
anti-c-Jun antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-c-Jun antibody    Western blot analysis of extracts from HeLa cells using c-Jun (Ab-243) antibody.
anti-c-Jun antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for c-Jun. It may not necessarily be applicable to this product.
 NCBI GI #    4758616
 NCBI GeneID    3725
 NCBI Accession #    NP_002219.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002228.3 [Other Products]
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 UniProt Primary Accession #    P05412 [Other Products]
 UniProt Secondary Accession #    Q6FHM7; Q96G93 [Other Products]
 UniProt Related Accession #    P05412 [Other Products]
 Molecular Weight    35,676 Da
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 NCBI Official Full Name    transcription factor AP-1
 NCBI Official Synonym Full Names    Jun proto-oncogene, AP-1 transcription factor subunit
 NCBI Official Symbol    JUN [Similar Products]
 NCBI Official Synonym Symbols   
AP1; p39; AP-1; c-Jun
[Similar Products]
 NCBI Protein Information    transcription factor AP-1
 UniProt Protein Name    Transcription factor AP-1
 UniProt Synonym Protein Names   
Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39
 Protein Family    C-Jun-amino-terminal kinase-interacting protein
 UniProt Gene Name    JUN [Similar Products]
 UniProt Synonym Gene Names    AP1 [Similar Products]
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 NCBI Summary for c-Jun    This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
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 UniProt Comments for c-Jun    Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
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Product References and Citations for anti-c-Jun antibody

   Boyle W J, et al. (1991) Cell. 64(3): 573-584. Binetruy B, et al. (1991) Nature. 351: 122-127. Smeal T, et al. (1991) Nature. 354:494-496. Derijard B, et al. (1994) Cell. 76:1025-1037. Kyriakis J M, et al. (1994) Nature. 369: 156-160.
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 Research Articles on c-Jun    1. Results show that VEGFA induces c-jun expression in mediating human retinal microvascular endothelial cell migration, sprouting and tube formation, and that Pyk2-STAT3 signaling enhances cJun expression in the mediation of retinal neovascularization.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-c-Jun antibodyPathways associated with anti-c-Jun antibody
 Reference Product  PubMed Publications
 FOS antibody  >7724 publications with c-Jun and FOS
 MAPK3 antibody  >1743 publications with c-Jun and MAPK3
 ITCH antibody  >1555 publications with c-Jun and ITCH
 STAT3 antibody  >1154 publications with c-Jun and STAT3
 SP1 antibody  >1117 publications with c-Jun and SP1
 CYP19A1 antibody  >1089 publications with c-Jun and CYP19A1
 JUNB antibody  >1007 publications with c-Jun and JUNB
 BRCA1 antibody  >838 publications with c-Jun and BRCA1
 MAPK8 antibody  >753 publications with c-Jun and MAPK8
 HIF1A antibody  >692 publications with c-Jun and HIF1A
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of The AP-1 Family Of Transcription Factors Pathway antibodies  Activation Of The AP-1 Family Of Transcription Factors Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
Diseases associated with anti-c-Jun antibodyOrgans/Tissues associated with anti-c-Jun antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >212671 publications with c-Jun and Neoplasms
 Nervous System Diseases Antibodies  >169822 publications with c-Jun and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >153114 publications with c-Jun and Cardiovascular Diseases
 Brain Diseases Antibodies  >80019 publications with c-Jun and Brain Diseases
 Heart Diseases Antibodies  >75539 publications with c-Jun and Heart Diseases
 Pain Antibodies  >48946 publications with c-Jun and Pain
 Liver Diseases Antibodies  >40433 publications with c-Jun and Liver Diseases
 Inflammation Antibodies  >37550 publications with c-Jun and Inflammation
 Kidney Diseases Antibodies  >34758 publications with c-Jun and Kidney Diseases
 Hypertension Antibodies  >31808 publications with c-Jun and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >287449 publications with c-Jun and Blood
 Brain Antibodies  >118368 publications with c-Jun and Brain
 Heart Antibodies  >92781 publications with c-Jun and Heart
 Vascular Antibodies  >83532 publications with c-Jun and Vascular
 Bone Antibodies  >80771 publications with c-Jun and Bone
 Liver Antibodies  >74113 publications with c-Jun and Liver
 Muscle Antibodies  >72042 publications with c-Jun and Muscle
 Lung Antibodies  >55937 publications with c-Jun and Lung
 Kidney Antibodies  >54571 publications with c-Jun and Kidney
 Skin Antibodies  >51525 publications with c-Jun and Skin
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