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anti-hnRNP H antibody :: Rabbit hnRNP H Antibody

Scan QR to view Datasheet Catalog #    MBS001847 anti-hnRNP H antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

hnRNP H, Antibody

 Also Known As   

Rabbit hnRNP H Antibody

 Product Gene Name   

anti-hnRNP H antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: X; NC_000023.10 (100663121..100669128). Location: Xq22
 OMIM    300610
 3D Structure    ModBase 3D Structure for P55795
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-hnRNP H antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-hnRNP H antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for hnRNP H. It may not necessarily be applicable to this product.
 NCBI GI #    74099697
 NCBI GeneID    3188
 NCBI Accession #    NP_001027565.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001032393.2 [Other Products]
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 UniProt Primary Accession #    P55795 [Other Products]
 UniProt Secondary Accession #    Q9HHA7; A1L400 [Other Products]
 UniProt Related Accession #    P55795 [Other Products]
 Molecular Weight    49,264 Da
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 NCBI Official Full Name    heterogeneous nuclear ribonucleoprotein H2
 NCBI Official Synonym Full Names    heterogeneous nuclear ribonucleoprotein H2 (H')
 NCBI Official Symbol    HNRNPH2 [Similar Products]
 NCBI Official Synonym Symbols   
FTP3; HNRPH'; HNRPH2; hnRNPH'
[Similar Products]
 NCBI Protein Information    heterogeneous nuclear ribonucleoprotein H2; FTP-3; hnRNP H'; hnRNP H2; heterogeneous nuclear ribonucleoprotein H-prime
 UniProt Protein Name    Heterogeneous nuclear ribonucleoprotein H2
 UniProt Synonym Protein Names   
FTP-3; Heterogeneous nuclear ribonucleoprotein H'
 UniProt Gene Name    HNRNPH2 [Similar Products]
 UniProt Synonym Gene Names    FTP3; HNRPH2; hnRNP H2; hnRNP H' [Similar Products]
 UniProt Entry Name    HNRH2_HUMAN
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 NCBI Summary for hnRNP H    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011]
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 UniProt Comments for hnRNP H    hnRNP H2: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).

Protein type: RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: nucleoplasm; membrane; nucleus; ribonucleoprotein complex

Molecular Function: RNA binding; nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression
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 Research Articles on hnRNP H    1. altered function of hnRNP H1/H2 in tumor cells is a novel determinant of aberrant thymidine phosphorylase splicing thereby resulting in acquired chemoresistance to TP-activated fluoropyrimidine anticancer drugs.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-hnRNP H antibodyDiseases associated with anti-hnRNP H antibody
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with hnRNP H and Liver Diseases
 Neoplasms Antibodies  >1 publications with hnRNP H and Neoplasms
Organs/Tissues associated with anti-hnRNP H antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with hnRNP H and Blood
 Brain Antibodies  >2 publications with hnRNP H and Brain
 Nerve Antibodies  >1 publications with hnRNP H and Nerve
 Muscle Antibodies  >1 publications with hnRNP H and Muscle
 Stomach Antibodies  >1 publications with hnRNP H and Stomach
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