Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow mGluR7  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • Troponin I (TN-I) ELISA Kit
 • AKT1 Antibody
 • Adrenocorticotropic Hormone (ACTH) ELISA Kit
 • zonulin ELISA Kit
 • Cyclin D2 (CCND2) Antibody
 • EYA3 Antibody
 • SLC2A5 Antibody
 • OSTEOCALCIN (Bglap2) Antibody
 • Plasma Renin Activity (PRA) ELISA Kit
 • Serine-threonine-protein kinase STK11 ELISA Kit
 • Herpes Simplex Virus 2 gC (HSV 2 gC) Antibody
 • Plasminogen Activator (PLGA) ELISA Kit
 • PIN1 Antibody
 • Axis Inhibition Protein (AXIN) ELISA Kit
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-mGluR7 antibody :: Rabbit mGluR7 Antibody

Scan QR to view Datasheet Catalog #    MBS853322
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

mGluR7, Antibody

★Popular Item★
 Also Known As   

mGluR7 Antibody

 Product Synonym Names    EAA5; GLR7; GluR7a; dJ1090M5.1 (glutamate receptor; ionotropic; kainate 3 (GLUR7)); excitatory amino acid receptor 5; glutamate receptor 7 precursor
 Product Gene Name   

anti-mGluR7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    604101
 3D Structure    ModBase 3D Structure for Q14831
Section Bar
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Specificity    GluR7 antibody detects endogenous levels of total GluR7 protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    100ug/100ul (lot specific)
Section Bar
 Immunogen    The antiserum was produced against synthesized peptide derived from human GluR7.
 Pathway    Channel
Section Bar
 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-mGluR7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-mGluR7 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-mGluR7 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-mGluR7 antibody    WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:20000
Section Bar
 Testing Data of anti-mGluR7 antibody    Peptide - +
Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR7 antibody (E11-0211C).
anti-mGluR7 antibody Testing Data image
Section Bar
 Testing Data #2 of anti-mGluR7 antibody    Western blot analysis of extracts from HuvEc cells, using GluR7 antibody (E11-0211C).
anti-mGluR7 antibody Testing Data #2 image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for mGluR7. It may not necessarily be applicable to this product.
 NCBI GI #    4504147
 NCBI GeneID    2917
 NCBI Accession #    NP_000835.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000844.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q14831 [Other Products]
 UniProt Secondary Accession #    Q8NFS2; Q8NFS3; Q8NFS4 [Other Products]
 UniProt Related Accession #    Q14831 [Other Products]
 Molecular Weight    101,302 Da
Table BarTOPTable Bar
 NCBI Official Full Name    metabotropic glutamate receptor 7 isoform a
 NCBI Official Synonym Full Names    glutamate receptor, metabotropic 7
 NCBI Official Symbol    GRM7 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    metabotropic glutamate receptor 7; protein phosphatase 1, regulatory subunit 87
 UniProt Protein Name    Metabotropic glutamate receptor 7
 UniProt Gene Name    GRM7 [Similar Products]
 UniProt Synonym Gene Names    GPRC1G; MGLUR7; mGluR7 [Similar Products]
 UniProt Entry Name    GRM7_HUMAN
Section Bar
 NCBI Summary for mGluR7    L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Section Bar
 UniProt Comments for mGluR7    mGluR7: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. Belongs to the G-protein coupled receptor 3 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 3

Chromosomal Location of Human Ortholog: 3p26.1-p25.1

Cellular Component: asymmetric synapse; presynaptic membrane; postsynaptic membrane; axon; integral to plasma membrane; dendrite; integral to membrane; presynaptic active zone; plasma membrane; dendritic shaft; cell cortex; receptor complex

Molecular Function: voltage-gated calcium channel activity; group III metabotropic glutamate receptor activity; glutamate binding; calcium channel regulator activity; calcium ion binding; glutamate receptor activity; PDZ domain binding

Biological Process: behavioral fear response; regulation of synaptic transmission, glutamatergic; negative regulation of glutamate secretion; short-term memory; sensory perception of smell; negative regulation of adenylate cyclase activity; regulation of cyclase activity; transmission of nerve impulse; synaptic transmission; negative regulation of cAMP biosynthetic process; sensory perception of sound; adult behavior; conditioned taste aversion; metabotropic glutamate receptor, adenylate cyclase inhibiting pathway
Table BarTOPTable Bar

Product References and Citations for anti-mGluR7 antibody

   Hans H. Schiffer, J. Neurosci., Dec 2000; 20: 9025.
Nathalie Strutz, J. Neurosci., Jan 2001; 21: 401.
Frİdİric Jaskolski, J. Biol. Chem., Jun 2005; 280: 22968 - 22976.
DE Hamassaki-Britto, J. Neurosci., May 1993; 13: 1888.
Section Bar
 Research Articles on mGluR7    1. For neither PCLO nor GRM7 we found a more associated variant. For SLC6A4, we found a new SNP that showed a lower P-value than in the GAIN-MDD GWAS
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-mGluR7 antibodyPathways associated with anti-mGluR7 antibody
 Reference Product  PubMed Publications
 GRM1 antibody  >2 publications with mGluR7 and GRM1
 GRIK1 antibody  >1 publications with mGluR7 and GRIK1
 GRIP1 antibody  >1 publications with mGluR7 and GRIP1
 GRM8 antibody  >1 publications with mGluR7 and GRM8
 GRM4 antibody  >1 publications with mGluR7 and GRM4
 Products by Pathway  Pathway Diagram
 Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway antibodies  Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class C Metabotropic Glutamate, Pheromone Pathway antibodies  GPCRs, Class C Metabotropic Glutamate, Pheromone Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with anti-mGluR7 antibodyOrgans/Tissues associated with anti-mGluR7 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with mGluR7 and Nervous System Diseases
 Attention Deficit Disorder with Hyperactivity Antibodies  >6 publications with mGluR7 and Attention Deficit Disorder with Hyperactivity
 Anxiety Disorders Antibodies  >4 publications with mGluR7 and Anxiety Disorders
 Brain Diseases Antibodies  >3 publications with mGluR7 and Brain Diseases
 Memory Disorders Antibodies  >2 publications with mGluR7 and Memory Disorders
 Substance-Related Disorders Antibodies  >2 publications with mGluR7 and Substance-Related Disorders
 Nerve Degeneration Antibodies  >1 publications with mGluR7 and Nerve Degeneration
 Developmental Disabilities Antibodies  >1 publications with mGluR7 and Developmental Disabilities
 Disease Models, Animal Antibodies  >1 publications with mGluR7 and Disease Models, Animal
 Movement Disorders Antibodies  >1 publications with mGluR7 and Movement Disorders
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >2 publications with mGluR7 and Mixed
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions