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anti-n-NOS antibody :: n-NOS Antibody

Scan QR to view Datasheet Catalog #    MBS859762
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

n-NOS, Antibody

★Popular Item★
 Also Known As   

n-NOS (Phospho-Ser852) Antibody

 Product Synonym Names    BNOS; Constitutive NOS; EC 1.14.13.39; N-NOS; NC-NOS; NOS; type I; NOS1; Neuronal NOS; Nitric-oxide synthase; brain; bNOS
 Product Gene Name   

anti-n-NOS antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P29476
 Species Reactivity    Human, Mouse, Rat
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 Specificity    n-NOS (Phospho-Ser852) antibody detects endogenous levels of n-NOS only when phosphorylated at serine 847.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized phosphopeptide derived from human n-NOS around the phosphorylation site of serine 847 (F-N-SP-V-S).
 All Sites    Human: Ser852
Mouse: Ser847
Rat: Ser847
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-n-NOS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-n-NOS antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-n-NOS antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-n-NOS antibody    WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000
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 Testing Data of anti-n-NOS antibody    P-peptide-+
anti-n-NOS antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-n-NOS antibody    Immunohistochemistry analysis of paraffin-embedded human brain tissue using n-NOS (Phospho-Ser852) antibody. Western blot analysis of extracts from A549 cells, using n-NOS (Phospho-Ser852) antibody.
anti-n-NOS antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-n-NOS antibody    P-peptide-+ Immunofluorescence analysis of HeLa cells, using n-NOS (Phospho-Ser852) antibody.
anti-n-NOS antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for n-NOS. It may not necessarily be applicable to this product.
 NCBI GI #    16258811
 NCBI GeneID    24598
 NCBI Accession #    NP_434686.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_052799.1 [Other Products]
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 UniProt Primary Accession #    P29476 [Other Products]
 UniProt Secondary Accession #    P70594 [Other Products]
 UniProt Related Accession #    P29476 [Other Products]
 Molecular Weight    164,430 Da
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 NCBI Official Full Name    nitric oxide synthase, brain
 NCBI Official Synonym Full Names    nitric oxide synthase 1
 NCBI Official Symbol    Nos1 [Similar Products]
 NCBI Official Synonym Symbols   
bNOS
[Similar Products]
 NCBI Protein Information    nitric oxide synthase, brain
 UniProt Protein Name    Nitric oxide synthase, brain
 UniProt Synonym Protein Names   
BNOS; Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Peptidyl-cysteine S-nitrosylase NOS1
 UniProt Gene Name    Nos1 [Similar Products]
 UniProt Synonym Gene Names    Bnos; N-NOS; nNOS [Similar Products]
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 NCBI Summary for n-NOS    enzyme that catalyzes the production of nitric oxide [RGD, Feb 2006]
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 UniProt Comments for n-NOS    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
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Product References and Citations for anti-n-NOS antibody

   George D. Webb, J. Thorac. Cardiovasc. Surg., Nov 2006; 132: 1131-1136. Montserrat García-Vitoria, J. Histochem. Cytochem., Aug 2000; 48: 1111. Peter J. Reiser, J Appl Physiol, Apr 1997; 82: 1250. VL Dawson, J. Neurosci., Apr 1996; 16: 2479.
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 Research Articles on n-NOS    1. we demonstrated a significant upregulation of nNOS expression, accompanied by significant increases in NOS activity and NO production, in the brain of rats exposed to simulated weightlessness.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-n-NOS antibodyPathways associated with anti-n-NOS antibody
 Reference Product  PubMed Publications
 Cav1 antibody  >7 publications with n-NOS and Cav1
 Grin2b antibody  >5 publications with n-NOS and Grin2b
 Dlg4 antibody  >2 publications with n-NOS and Dlg4
 Ass1 antibody  >1 publications with n-NOS and Ass1
 Dlg1 antibody  >1 publications with n-NOS and Dlg1
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Diseases associated with anti-n-NOS antibodyOrgans/Tissues associated with anti-n-NOS antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >541 publications with n-NOS and Nervous System Diseases
 Brain Diseases Antibodies  >294 publications with n-NOS and Brain Diseases
 Mental Disorders Antibodies  >187 publications with n-NOS and Mental Disorders
 Hypertension Antibodies  >172 publications with n-NOS and Hypertension
 Inflammation Antibodies  >153 publications with n-NOS and Inflammation
 Heart Diseases Antibodies  >108 publications with n-NOS and Heart Diseases
 Pain Antibodies  >105 publications with n-NOS and Pain
 Anoxia Antibodies  >101 publications with n-NOS and Anoxia
 Kidney Diseases Antibodies  >61 publications with n-NOS and Kidney Diseases
 Schizophrenia Antibodies  >55 publications with n-NOS and Schizophrenia
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >532 publications with n-NOS and Muscle
 Testis Antibodies  >7 publications with n-NOS and Testis
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