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anti-nNOS antibody :: Rabbit nNOS Antibody

Scan QR to view Datasheet Catalog #    MBS9382700
Western blot
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

nNOS, Antibody

★Popular Item★
 Also Known As   

nNOS Antibody

 Product Gene Name   

anti-nNOS antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS9382700 Technical Datasheet    Technical Datasheet PDF
 OMIM    U17327 mRNA
 3D Structure    ModBase 3D Structure for P29475
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 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    nNOS Antibody detects endogenous levels of total nNOS
 Purity/Purification    Immunogen affinity purified
 Concentration    1.0mg/ml (lot specific)
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 Immunogen    A synthesized peptide derived from human nNOS
 Buffer    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Preparation and Storage    Store at -20 C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-nNOS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-nNOS antibody

   nNOS nitric oxide synthase 1, neuronal form. Produces nitric oxide which is a messenger molecule with diverse functions and displays many properties of a neurotransmitter in the brain and peripheral nervous system. May be an effector enzyme for the dystrophin complex.
 Applications Tested/Suitable for anti-nNOS antibody   

Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

 Application Notes for anti-nNOS antibody    WB 1:500-1:2000
IF/ICC 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
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 Western blot of anti-nNOS antibody    Western blot analysis of nNOS expression in INF treated RAW264.7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
anti-nNOS antibody Western blot image
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NCBI/Uniprot data below describe general gene information for nNOS. It may not necessarily be applicable to this product.
 NCBI GI #    10835173
 NCBI GeneID    4842
 NCBI Accession #    NP_000611.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000620.4 [Other Products]
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 UniProt Primary Accession #    P29475 [Other Products]
 UniProt Secondary Accession #    O75713; E9PH30 [Other Products]
 UniProt Related Accession #    P29475 [Other Products]
 Molecular Weight    120kDa
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 NCBI Official Full Name    nitric oxide synthase, brain isoform 1
 NCBI Official Synonym Full Names    nitric oxide synthase 1
 NCBI Official Symbol    NOS1 [Similar Products]
 NCBI Official Synonym Symbols   
NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS
[Similar Products]
 NCBI Protein Information    nitric oxide synthase, brain
 UniProt Protein Name    Nitric oxide synthase, brain
 UniProt Synonym Protein Names   
Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Peptidyl-cysteine S-nitrosylase NOS1; bNOS
 UniProt Gene Name    NOS1 [Similar Products]
 UniProt Synonym Gene Names    N-NOS; nNOS [Similar Products]
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 NCBI Summary for nNOS    The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
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 UniProt Comments for nNOS    nNOS: nitric oxide synthase 1, neuronal form. Produces nitric oxide which is a messenger molecule with diverse functions and displays many properties of a neurotransmitter in the brain and peripheral nervous system. May be an effector enzyme for the dystrophin complex. Four alternatively spliced isoforms have been described.

Protein type: Amino Acid Metabolism - arginine and proline; EC 1.14.13.39; Oxidoreductase

Chromosomal Location of Human Ortholog: 12q24.22

Cellular Component: cytoplasm; cytoskeleton; cytosol; lipid raft; mitochondrion; perinuclear region of cytoplasm; photoreceptor inner segment; protein complex; sarcolemma; sarcoplasmic reticulum; synapse

Molecular Function: cadmium ion binding; FAD binding; FMN binding; heme binding; NADP binding; nitric-oxide synthase activity; protein binding; sodium channel regulator activity

Biological Process: arginine catabolic process; cell redox homeostasis; exogenous drug catabolic process; multicellular organismal response to stress; myoblast fusion; negative regulation of blood pressure; negative regulation of calcium ion transport; negative regulation of hydrolase activity; negative regulation of potassium ion transport; negative regulation of serotonin uptake; neurotransmitter biosynthetic process; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; peptidyl-cysteine S-nitrosylation; positive regulation of guanylate cyclase activity; positive regulation of histone acetylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of vasodilation; regulation of sodium ion transport; response to heat; response to hypoxia; striated muscle contraction

Disease: Pyloric Stenosis, Infantile Hypertrophic, 1
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 Research Articles on nNOS    1. The found of this study suggested that possible roles of NOS1 gene in working memory performance in ADHD patients
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-nNOS antibodyPathways associated with anti-nNOS antibody
 Reference Product  PubMed Publications
 HMOX1 antibody  >13 publications with nNOS and HMOX1
 NOS1AP antibody  >9 publications with nNOS and NOS1AP
 CAV3 antibody  >7 publications with nNOS and CAV3
 ADRA1B antibody  >6 publications with nNOS and ADRA1B
 ADRA1A antibody  >6 publications with nNOS and ADRA1A
 ARG1 antibody  >5 publications with nNOS and ARG1
 DYNLL1 antibody  >5 publications with nNOS and DYNLL1
 NOSIP antibody  >3 publications with nNOS and NOSIP
 DLG4 antibody  >2 publications with nNOS and DLG4
 CAMK4 antibody  >2 publications with nNOS and CAMK4
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Diseases associated with anti-nNOS antibodyOrgans/Tissues associated with anti-nNOS antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >465 publications with nNOS and Nervous System Diseases
 Brain Diseases Antibodies  >251 publications with nNOS and Brain Diseases
 Disease Models, Animal Antibodies  >208 publications with nNOS and Disease Models, Animal
 Hypertension Antibodies  >147 publications with nNOS and Hypertension
 Mental Disorders Antibodies  >138 publications with nNOS and Mental Disorders
 Drug Toxicity Antibodies  >124 publications with nNOS and Drug Toxicity
 Inflammation Antibodies  >121 publications with nNOS and Inflammation
 Brain Ischemia Antibodies  >102 publications with nNOS and Brain Ischemia
 Pain Antibodies  >88 publications with nNOS and Pain
 Heart Diseases Antibodies  >87 publications with nNOS and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1061 publications with nNOS and Brain
 Muscle Antibodies  >458 publications with nNOS and Muscle
 Lung Antibodies  >76 publications with nNOS and Lung
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