CAA38587.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,999 Da
NCBI Official Full Name
alpha-1-microglobulin, partial
NCBI Official Synonym Full Names
alpha-1-microglobulin/bikunin precursor
NCBI Official Synonym Symbols
A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC [Similar Products]
NCBI Protein Information
protein AMBP
UniProt Protein Name
Protein AMBP
UniProt Synonym Protein Names
Alpha-1-microglobulin; Protein HC
UniProt Synonym Gene Names
UniProt Entry Name
AMBP_HUMAN
NCBI Summary for AMBP
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]
UniProt Comments for AMBP
AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q32-q33
Cellular Component: cell surface; extracellular region; extracellular space; intracellular membrane-bound organelle; plasma membrane
Molecular Function: calcium channel inhibitor activity; calcium oxalate binding; heme binding; IgA binding; protein binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity
Biological Process: cell adhesion; female pregnancy; heme catabolic process; negative regulation of immune response; negative regulation of JNK cascade; protein catabolic process; protein-chromophore linkage; receptor-mediated endocytosis; viral reproduction
Research Articles on AMBP
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Products associated with AMBP antigen
Pathways associated with AMBP antigen
Diseases associated with AMBP antigen
Organs/Tissues associated with AMBP antigen
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