P01876.2
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UniProt Related Accession #
Molecular Weight
37,655 Da
NCBI Official Full Name
Ig alpha-1 chain C region, partial
NCBI Official Synonym Full Names
immunoglobulin heavy constant alpha 1
NCBI Official Synonym Symbols
UniProt Protein Name
Ig alpha-1 chain C region
UniProt Entry Name
IGHA1_HUMAN
UniProt Comments for IgA
IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
Protein type: Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: antigen binding
Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
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Pathways associated with IgA antigen
Organs/Tissues associated with IgA antigen
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