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Radius 24-Well Cell Migration Assay, (ECM Array Coated) Assay Kit

Scan QR to view Datasheet Catalog #    MBS169144
Unit / Price
24 Wells  /  $645 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Radius 24-Well Cell Migration Assay, (ECM Array Coated), Assay Kit

 Also Known As   

Radius 24-Well Cell Migration Assay, (ECM Array Coated)

 Product Synonym Names    Radius 24-Well Cell Migration Assay, (ECM Array Coated)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
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 Preparation and Storage    Upon receipt, aliquot and store the Radius Gel Removal Solution and DAPI Fluorescence Stain at -20 degree C (avoid multiple freeze/thaw cycles), and transfer the Fixation Solution to 4 degree C. All other kit components should be stored at room temperature until the kit's expiration date.
 Product Note    Our Assay Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit

   Background: Cell migration is a highly integrated, multistep process that orchestrates embryonic morphogenesis, tissue repair and regeneration. It plays a pivotal role in the disease progression of cancer, mental retardation, atherosclerosis, and arthritis. The initial response of a cell to a migration-promoting agent is to polarize and extend protrusions in the direction of the attractant; these protrusions can consist of large, broad lamellipodia or spike-like filopodia. In either case, these protrusions are driven by actin polymerization and can be stabilized by extracellular matrix (ECM) adhesion or cell-cell interactions (via transmembrane receptors). The Radius Cell Migration Assay Kit utilizes a proprietary 24-well plate, which has been pre-coated with various ECM proteins (see Migration Plate Layout below), to monitor the migratory properties of cells. Each plate well contains a 0.68 mm non-toxic, biocompatible hydrogel spot (Radius Gel) where cells cannot attach. When adherent cells are seeded in the Radius Cell Migration well, they attach outside of the Radius Gel coated area. Once firm cell attachment is achieved, the hydrogel is quickly removed to expose a cell-free region to study cell migration/closure. This format provides a robust in vitro system to measure 2-D cell migration, screen potential inhibitors and study cytoskeleton reorganization events. The Radius Cell Migration Assay Kit is designed for High Content Analysis applications or imaging software and is adaptable to liquid handling equipment. Each kit provides sufficient quantities to perform 24 migration tests (18 ECM protein-coated wells, 6 uncoated wells).
 Product Categories/Family for Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit    Cell Based Assays; Cell Migration; Invasion and Wound Healing; Gap Closure Assays; Cell Migration Assays; 2D Gap Closure
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 Testing Data of Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit    Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit Testing Data image
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 Testing Data #2 of Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit    Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit Testing Data #2 image
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 Testing Data #3 of Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit    Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit Testing Data #3 image
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 Testing Data #4 of Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit    Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit Testing Data #4 image
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Sample Manual Insert of MBS169144. Click to request current manual
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Product References and Citations for Radius 24-Well Cell Migration Assay, (ECM Array Coated) assay kit

   1. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. (2003) Science 302, 1704-9.
2. Horwitz R, Webb D. (2003) Curr Biol. 13, R756-9.
3. Lauffenburger DA, Horwitz AF. (1996) Cell 84, 359-369.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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