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A-366 biochemical

Scan QR to view Datasheet Catalog #    MBS842453
Unit / Price
1 mg  /  $155 +1 FREE 8GB USB
5 mg  /  $430 +1 FREE 8GB USB
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 Product Name   

A-366, Biochemical

 Also Known As   


 Product Synonym Names    5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine
 Product Gene Name   

A-366 biochemical

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Purity/Purification    >=98% by HPLC
 Form/Format    Appearance: Off-white solid
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 CAS Number    1527503-11-2
 Structure Available?    Yes
 Salt Form    No
 Cell-Permeable?    Yes
 Solubility/Reconstitution Instructions    DMSO (>25 mg/ml)
 InChi    InChI=1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)
 Handling    Protect from air and light
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 Preparation and Storage    At -20 degree C
Shelf Life: 36 months
 Other Notes    Small volumes of A-366 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for A-366 biochemical

   Background: A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC?? = 3.3 nM). It displays >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. A-366 has been shown to inhibit H3K9 methylation in prostate cancer PC3 cells with an IC?? of 100 nM.
 Product Categories/Family for A-366 biochemical    Enzyme Inhibitors; Methyltransferase InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z)Biochemicals; Enzyme Inhibitors; Methyltransferase InhibitorsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z)Epigenetics; Writer Enzymes; Protein Lysine Methy
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 Structure of A-366 biochemical    A-366 biochemical Structure image
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 Molecular Weight    329.44
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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