View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List A 83-01 biochemical Catalog # MBS842636 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name A 83-01, Biochemical Full Product Name A 83-01 Product Synonym Names 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-p yrazole-1-carbothioamide Product Gene Name A 83-01 biochemical[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Purity/Purification >=98% by HPLC Form/Format Appearance: Pale yellow solid CAS Number 909910-43-6 Structure Available? Yes Salt Form No Cell-Permeable? Yes MDL Number MFCD08705403 PubChem CID 16218924 Solubility/Reconstitution Instructions DMSO SMILES CC1=CC=CC(=N1)C2=NN(C=C2C3=CC=NC4=CC=CC=C34)C(=S)NC5=CC=CC=C5 InChi InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31) InChi Key HIJMSZGHKQPPJS-UHFFFAOYSA-N Handling Protect from air and light Preparation and Storage At -20 degree CShelf Life: 24 months Other Notes Small volumes of A 83-01 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for A 83-01 biochemical Background: A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC?? values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs). Product Categories/Family for A 83-01 biochemical Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Biochemicals (A-Z) Structure of A 83-01 biochemical TOP Molecular Weight 421.52 TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP