Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Biochemical rightarrow AAL-993  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • KRT7 Antibody
 • Complement Factor H Related Protein 3 (CFHR3) ELISA Kit
 • FLNbeta ELISA Kit
 • ATR Antibody
 • Prostate Specific Antigen (PSA) Total (KLK3) Antibody
 • pyridoxal (pyridoxine, vitamin B6) kinase (PDXK) ELISA Kit
 • COP9 signalosome complex subunit 2 (COPS2) Recombinant Protein
 • Fc fragment of IgG, receptor, transporter, alpha (FCGRT) Antibody
 • p57Kip2 (CDKN1C) Antibody
 • Tropomyosin (TM1) Recombinant Protein
 • Ezrin Antibody
 • Regenerating Islet Derived Protein 3 Alpha (REG3a) Antibody
 • COL6alpha1 ELISA Kit
 • Glucocorticoid Receptor (NR3C1) Antibody
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

AAL-993 biochemical

Scan QR to view Datasheet Catalog #    MBS842171
Unit / Price
2 mg  /  $145 +1 FREE 8GB USB
10 mg  /  $385 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AAL-993, Biochemical

 Also Known As   


 Product Synonym Names    2-((4-Pyridyl)methyl)amino-N-(3-(trifluoromethyl)phenyl)benzamide
 Product Gene Name   

AAL-993 biochemical

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
Section Bar
 Purity/Purification    >=98% by TLC
 Form/Format    Appearance: Light yellow solid
Section Bar
 CAS Number    269390-77-4
 Structure Available?    Y
 Salt Form    No
 Cell-Permeable?    Yes
 PubChem CID    6398883
 Solubility/Reconstitution Instructions    DMSO (>25 mg/ml) or EtOH (~15 mg/ml)
 SMILES    C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC=NC=C3
 InChi    InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
 Handling    Protect from air and light
Section Bar
 Preparation and Storage    At -20 degree C
Shelf Life: 36 months
 Other Notes    Small volumes of AAL-993 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar

Related Product Information for AAL-993 biochemical

   Background: AAL-993 is a potent, selective and cell-permeable inhibitor of VEGFR-1 (IC?? = 130 nM), VEGFR-2 (IC?? = 23 nM) and VEGFR-3 (IC?? = 18nM). At higher concentrations it inhibits PDGFR (640 nM), c-Kit (236 nM) and CSF-1R (380 nM). Inactive at other kinases such as EGFR, FGFR-1, CDK-1, Tie-2, c-Met, IGF-1R, c-Src and c-Abl. X-ray crystal studies on AAL-993 complexed to the catalytic domain of diphosphorylated VEGFR- 2 indicates that it binds to an inactive conformation of the protein. AAL-993 inhibits VEGF-induced angiogenesis (mouse model).
 Product Categories/Family for AAL-993 biochemical    Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Biochemicals (A-Z)
Section Bar
 Structure of AAL-993 biochemical    AAL-993 biochemical Structure image
Table BarTOPTable Bar
 Molecular Weight    371.36
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions