View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List Eeyarestatin I Biochemical Catalog # MBS845782 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Eeyarestatin I, Biochemical Full Product Name Eeyarestatin I Product Synonym Names 3- (4-Chlorophenyl)-4-[[[ (4-chlorophenyl) amino]carbonyl]hydroxyamino]-5; 5-dimethyl-2-oxo-1-imidazolidineacetic acid 2-[3- (5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Purity/Purification >=98% by HPLC Form/Format White to off-white solid Salt Form No Molecular Formula C27H25Cl2N7O7 CAS Number 412960-54-4 Cell-Permeable Yes Reconstitution DMSO (>30 mg/ml) SMILES CC1(C(N(C(=O)N1CC(=O)NN=CC=CC2=CC=C(O2)[N+](=O)[O-])C3=CC=C(C=C3)Cl)N(C(=O)NC4=CC=C(C=C4)Cl)O)C InChi InChI=1S/C27H25Cl2N7O7/c1-27(2)24(35(40)25(38)31-19-9-5-17(28)6-10-19)34(20-11-7-18(29)8-12-20)26(39)33(27)16-22(37)32-30-15-3-4-21-13-14-23(43-21)36(41)42/h3-15,24,40H,16H2,1-2H3,(H,31,38)(H,32,37)/b4-3+,30-15+ InChi Key JTUXTPWYZXWOIB-LWWHHIEBSA-N Preparation and Storage Store at -20 degree C for 36 months.Protect from air and light. Other Notes Small volumes of Eeyarestatin I biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Eeyarestatin I biochemical Eeyarestatin I is an inhibitor of the ERAD (Endoplasmic-reticulum-associated protein degradation) pathway; blocking the degradation of misfolded proteins at a dose of 8 uM. It associates with the p97-associated deubiquitinating complex in cells; preventing deubiquitination of substrates by ataxin-3 (atx3). Also inhibits Sec61-mediated protein translocation at the ER. Displays cytotoxic activity preferentially against cancer cells; induces cell death via the pro-apoptotic protein NOXA. Structure of Eeyarestatin I biochemical TOP Molecular Weight 630.44[Similar Products] TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP