View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List IC261 biochemical Catalog # MBS845848 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IC261, Biochemical Full Product Name IC261 Product Synonym Names (E)-3- (2; 4; 6-trimethoxybenzylidene) indolin-2-one; SU-5607 Product Gene Name IC261 biochemical[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Purity/Purification >=98% by HPLC Form/Format Yellow solid Salt Form No Molecular Formula C18H17NO4 CAS Number 186611-52-9 Cell-Permeable Yes Reconstitution DMSO (>10 mg/ml) SMILES COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC InChi InChI=1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20) InChi Key JBJYTZXCZDNOJW-UHFFFAOYSA-N Preparation and Storage Store at -20 degree C for 36 months.Protect from air and light. Other Notes Small volumes of IC261 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for IC261 biochemical IC261 is a reversible; ATP-competitive inhibitor of casein kinase 1 (CK1) (IC50 = ~1 uM for CK1delta and CK1epsilon and 16 uM for CK1alpha). It is at least 100-fold less effective against PKA; p34cdc2; and p55fyn. IC261; at 1 uM; inhibits cytokinesis in primary mouse embryo fibroblasts. IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1delta/epsilon and Wnt/beta-catenin independent inhibition of mitotic spindle formation. Structure of IC261 biochemical TOP Molecular Weight 311.34 TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP