View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List JNJ-26854165 biochemical Catalog # MBS842698 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name JNJ-26854165, Biochemical Full Product Name JNJ-26854165 Product Synonym Names 1-N-[2-(1H-indol-3-yl)ethyl]-4-N-pyridin-4-ylbenzene-1,4-diamine; Serdemetan Product Gene Name JNJ-26854165 biochemical[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Purity/Purification >=98% by HPLC Form/Format Appearance: Off-white solid CAS Number 881202-45-5 Structure Available? Yes Cell-Permeable? Yes PubChem CID 11609586 Solubility/Reconstitution Instructions DMSO (>50 mg/ml) SMILES C1=CC=C2C(=C1)C(=CN2)CCNC3=CC=C(C=C3)NC4=CC=NC=C4 InChi InChI=1S/C21H20N4/c1-2-4-21-20(3-1)16(15-24-21)9-14-23-17-5-7-18(8-6-17)25-19-10-12-22-13-11-19/h1-8,10-13,15,23-24H,9,14H2,(H,22,25) InChi Key CEGSUKYESLWKJP-UHFFFAOYSA-N Handling Protect from air and light Preparation and Storage At -20 degree CShelf Life: 24 months Other Notes Small volumes of JNJ-26854165 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for JNJ-26854165 biochemical Background: A novel p53-activating tryptamine derivative that acts as a HDM2 (Human Double Minute-2) antagonist with potential antineoplastic activity. JNJ-26854165 inhibits the binding of the HDM2-p53 complex to the proteasome, blocking the degradation of p53. It displays potent anti-proliferative and apoptosis-inducing activity in a broad range of p53 wild type and mutant tumor models. Product Categories/Family for JNJ-26854165 biochemical Enzyme Inhibitors; MDM2 Inhibitors and Biochemicals; Enzyme Inhibitors and Apoptosis & Related Products; Apoptosis Inducers and Biochemicals; Biochemicals (A-Z) Structure of JNJ-26854165 biochemical TOP Molecular Weight 328.41 TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP