P34969.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,984 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 7
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 7
NCBI Official Synonym Symbols
NCBI Protein Information
5-hydroxytryptamine receptor 7
UniProt Protein Name
5-hydroxytryptamine receptor 7
UniProt Synonym Protein Names
5-HT-X; Serotonin receptor 7
UniProt Synonym Gene Names
UniProt Entry Name
5HT7R_HUMAN
NCBI Summary for HTR7
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
UniProt Comments for HTR7
5-HT(7): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR
Chromosomal Location of Human Ortholog: 10q21-q24
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: serotonin receptor activity
Biological Process: blood circulation; circadian rhythm; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor signaling pathway; smooth muscle contraction; synaptic transmission; vasoconstriction
Research Articles on HTR7
Precautions
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Disclaimer
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Pathways associated with HTR7 blocking peptide
Diseases associated with HTR7 blocking peptide
Organs/Tissues associated with HTR7 blocking peptide
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